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首页> 外文期刊>Nordic journal of psychiatry. >The first 38 methadone maintenance treatment patients in Stockholm: 15-year follow-up with a main focus on detoxification from methadone.
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The first 38 methadone maintenance treatment patients in Stockholm: 15-year follow-up with a main focus on detoxification from methadone.

机译：斯德哥尔摩的首批38名美沙酮维持治疗患者：15年的随访，主要关注美沙酮的排毒。

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BACKGROUND/AIMS: The present study investigated the first 38 methadone maintenance treatment (MMT) patients in Stockholm. The aim was: (i) to investigate the possible predictive factors for successful treatment termination, and (ii) the long-term outcome effects and life situation of MMT patients and those who terminated the treatment. METHODS: The patients were interviewed at the start and approximately 15 years later, and divided into four groups: (1) no withdrawal attempts, (2) forced to stop the treatment, (3) successful tapering and (4) non-successful tapering. RESULTS: The predictive factor found that Group 1 showed a lower life quality compared with Groups 3 and 4. Fifteen years later, the life situations of Groups 3 and 4 were significantly more stable. Also the subjective well-being in Group 3 was significantly higher. Over all, Group 2 showed significantly more illicit drug use compared with Group 3. The social life situation was significantly improved for all patients during the 15 years. CONCLUSION: This study confirms our earlier findings that the ultimate goal of MMT for the motivated patients with good progress should be an opiate-free life. The life situation and subjective well-being seems to be higher after successful termination of MMT.
机译：背景/目的：本研究调查了斯德哥尔摩的首批38名美沙酮维持治疗（MMT）患者。目的是：（i）研究成功终止治疗的可能预测因素，以及（ii）MMT患者和终止治疗的患者的长期结果影响和生活状况。方法：患者在开始时和大约15年后进行了访谈，分为四组：（1）没有停药尝试，（2）被迫停止治疗，（3）成功减量和（4）减量不成功。结果：预测因素发现，第1组的生活质量比第3和第4组低。十五年后，第3和第4组的生活状况更加稳定。第三组的主观幸福感也明显更高。总体而言，与第3组相比，第2组显示出更多的非法药物使用。在15年中，所有患者的社交生活状况均得到明显改善。结论：这项研究证实了我们较早的发现，对于进展良好，积极主动的患者，MMT的最终目标应该是无鸦片生活。 MMT成功终止后，生活状况和主观幸福感似乎更高。

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