Bacterial 5S rRNA- Binding Proteins of the CTC Family

G. M. Gongadze; A. P. Korepanov; A. V. Korobeinikova

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Bacterial 5S rRNA- Binding Proteins of the CTC Family

机译：CTC家族的细菌5S rRNA结合蛋白

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The presence of CTC family proteins is a unique feature of bacterial cells. In the CTC family, there are true ribo-somal proteins (found in ribosomes of exponentially growing cells), and at the same time there are also proteins temporarily associated with the ribosome (they are produced by the cells under stress only and incorporate into the ribosome). One feature is common for these proteins - they specifically bind to 5S rRNA. In this review, the history of investigations of the best known representatives of this family is described briefly. Structural organization of the CTC family proteins and their occurrence among known taxonomic bacterial groups are discussed. Structural features of 5S rRNA and CTC protein are described that predetermine their specific interaction. Taking into account the position of a CTC protein and its intermol-ecular contacts in the ribosome, a possible role of its complex with 5S rRNA in ribosome functioning is discussed.

机译：CTC家族蛋白的存在是细菌细胞的独特特征。在CTC家族中，存在真正的核糖体蛋白（在呈指数增长的细胞的核糖体中发现），同时也存在暂时与核糖体相关的蛋白（它们仅在压力下由细胞产生并整合到核糖体中）。核糖体）。这些蛋白质共有一个特征-它们特异性结合5S rRNA。在这篇评论中，简要介绍了该家族最著名代表的调查历史。讨论了CTC家族蛋白的结构组织及其在已知分类细菌群中的出现。描述了5S rRNA和CTC蛋白的结构特征，可预先确定它们的特异性相互作用。考虑到CTC蛋白的位置及其在核糖体中的分子间接触，讨论了其与5S rRNA的复合体在核糖体功能中的可能作用。

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《Biochemistry》 |2008年第12期|共13页
作者
G. M. Gongadze; A. P. Korepanov; A. V. Korobeinikova;
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正文语种 eng
中图分类生物化学;
关键词
5S rRNA-binding proteins; CTC proteins; ribosome; translation; Bacteria;

机译：5S rRNA结合蛋白;CTC蛋白;核糖体;翻译;细菌;

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3. Bacterial 5S rRNA- Binding Proteins of the CTC Family [J] . G. M. Gongadze, A. P. Korepanov, A. V. Korobeinikova Biochemistry . 2008,第12期

机译：CTC家族的细菌5S rRNA结合蛋白
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机译：抗凋亡Bcl-2家族蛋白的广谱小分子抑制剂的设计，合成和活性评估：广谱蛋白结合的特征及其对抗肿瘤活性的影响
7. Analysis of the Unique Binding Interactions within the 5S Ribonucleoprotein Particle (5S RNP) in Trypanosoma brucei. [D] . Kamina, Anyango D. 2018

机译：布氏锥虫5S核糖蛋白颗粒（5S RNP）中独特的结合相互作用的分析。
8. Non-canonical binding interactions of the RNA recognition motif (RRM) domains of P34 protein modulate binding within the 5S ribonucleoprotein particle (5S RNP) [O] . Anyango D. Kamina, Noreen Williams -1

机译：P34蛋白的RNA识别基序（RRM）域的非规范结合相互作用可调节5S核糖蛋白颗粒（5S RNP）内的结合
9. Non-canonical binding interactions of the RNA recognition motif (RRM) domains of P34 protein modulate binding within the 5S ribonucleoprotein particle (5S RNP). [O] . Anyango D Kamina, Noreen Williams 2017

机译：p34蛋白的RNa识别基序（RRm）结构域的非规范结合相互作用调节5s核糖核蛋白颗粒（5s RNp）内的结合。

Bacterial 5S rRNA- Binding Proteins of the CTC Family

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