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Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: A review

机译:槟榔生物碱对精神分裂症阳性和阴性症状的潜在作用:综述

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Background: The Areca catechu Linn. is the fourth most used drug in the world after nicotine, ethanol and caffeine. This plant contains nine alkaloids with muscarinic and nicotinic action, which could have an antipsychotic effect. Aim: The aim of this work is reviewing literature data about the potential action of betel alkaloids on positive, negative and cognitive symptoms of schizophrenia. Method: We reviewed the clinical literature data since 1980 via a PubMed search for the terms: arecoline, arecaidine, guvacine, guvacoline, betel, Areca catechu, positive and negative symptoms, cognitive symptoms, psychosis and schizophrenia in combination. Conclusion: Male high consumption of betel had significantly lower positive symptoms than low consumers or non-betel users.
机译:背景:槟榔槟榔。是继尼古丁,乙醇和咖啡因之后的第四大最常用药物。该植物含有九种具有毒蕈碱和烟碱作用的生物碱,可能具有抗精神病作用。目的:这项工作的目的是回顾有关槟榔生物碱对精神分裂症的阳性,阴性和认知症状的潜在作用的文献资料。方法:自1980年以来,我们通过PubMed搜索以下术语回顾了临床文献数据:槟榔碱,槟榔碱,番石榴碱,番石榴碱,槟榔,槟榔槟榔,阳性和阴性症状,认知症状,精神病和精神分裂症。结论:男性高消费槟榔比低消费或非槟榔食用者的阳性症状明显降低。

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