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首页> 外文期刊>Nordic journal of psychiatry. >Is there an association between subjective and objective measures of cognitive function in patients with affective disorders?
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Is there an association between subjective and objective measures of cognitive function in patients with affective disorders?

机译：情感障碍患者的认知功能的主观和客观指标之间是否存在关联？

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Background: Patients with affective disorders experience cognitive dysfunction in addition to their affective symptoms. The relationship between subjectively experienced and objectively measured cognitive function is controversial with several studies reporting no correlation between subjective and objective deficits. Aims: To investigate whether there is a correlation between subjectively reported and objectively measured cognitive function in patients with affective disorders, and whether subjective complaints predict objectively measured dysfunction. Methods: The study included 45 participants; 15 with bipolar disorder (BD), 15 with unipolar disorder (UD) and 15 healthy individuals. Participants' subjectively experienced cognitive function and objective cognitive function were assessed with the Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire (CPFQ) and the Screen for Cognitive Impairment in Psychiatry (SCIP), respectively. Patients were rated for affective symptoms with Hamilton Depression Rating Scale (HDRS) and Young Mania Rating Scale (YMRS). Results: Patients demonstrated subjective and objective cognitive dysfunction relative to controls (P-values ≤ 0.01) but there were no differences between patient groups (P > 0.1). We found no correlation between subjectively experienced and objectively measured cognitive dysfunction in BD (P 0.7), and a non-significant trend towards a correlation in UD (P 0.06), which disappeared when controlling for gender (P 0.1). Conclusion: Our results suggest that it is not necessarily patients who have cognitive complaints that are most impaired. If confirmed in a larger sample, our findings suggest that neuropsychological assessment is warranted to elucidate the potential role of cognitive dysfunction in patients' everyday lives and to inform treatment strategies targeting these difficulties.
机译：背景：患有情感障碍的患者除了会出现情感症状外，还会出现认知功能障碍。主观经历和客观测量的认知功能之间的关系存在争议，一些研究报告说主观和客观缺陷之间没有相关性。目的：调查情感障碍患者的主观报告和客观测量的认知功能之间是否存在相关性，以及主观主诉是否预测客观测量的功能障碍。方法：该研究包括45名参与者。 15名患有双相情感障碍（BD），15名患有单相情感障碍（UD）和15位健康个体。参与者的主观经历的认知功能和客观认知功能分别通过马萨诸塞州综合医院认知和身体功能调查表（CPFQ）和精神病学认知障碍筛查（SCIP）进行评估。用汉密尔顿抑郁量表（HDRS）和年轻躁狂症量表（YMRS）对患者的情感症状进行评估。结果：相对于对照组，患者表现出主观和客观的认知功能障碍（P值≤0.01），但两组之间没有差异（P> 0.1）。我们发现BD的主观经历和客观测量的认知功能障碍之间无相关性（P 0.7），UD的相关性无明显趋势（P 0.06），在控制性别时消失了（P 0.1）。结论：我们的结果表明，认知障碍最严重的不一定是患者。如果在更大的样本中得到证实，我们的发现表明，应进行神经心理学评估来阐明认知功能障碍在患者日常生活中的潜在作用，并为针对这些困难的治疗策略提供依据。

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