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首页> 外文期刊>Nordic journal of psychiatry. >Environmental risk factors and their impact on the age of onset of schizophrenia: Comparing familial to non-familial schizophrenia
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Environmental risk factors and their impact on the age of onset of schizophrenia: Comparing familial to non-familial schizophrenia

机译：环境危险因素及其对精神分裂症发作年龄的影响：家族性精神分裂症与非家族性精神分裂症的比较

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Background and aims: Several risk factors for schizophrenia have yet been identified. The aim of our study was to investigate how certain childhood and adolescent risk factors predict the age of onset of psychosis in patients with and without a familial component (i.e. a relative with schizophrenia or schizoaffective disorder). Methods: Aside from the age of onset of psychosis, we examined the risk factors for schizophrenia including obstetric complications, birth during winter or spring, behavioral deviances or delayed motor and speech development, exposure to adverse life events and exposure to substance use within a group of 100 patients (45 female, 55 male) with a mean age (± standard deviation) of 35.15 ± 13.21. Results: Birth complications and cannabis abuse are predictors for an earlier onset of schizophrenia in patients with non-familial schizophrenia. No environmental risk factors for an earlier age of onset in familial schizophrenia have been identified. Conclusions: Certain environmental risk factors for schizophrenia seem to have an impact on the age of onset of psychosis in non-familial schizophrenia, they do not seem to have an impact on familial schizophrenia.
机译：背景和目的：精神分裂症的几种危险因素尚未确定。我们研究的目的是调查某些儿童期和青少年期的危险因素如何预测有或没有家族成分的患者（即患有精神分裂症或精神分裂症的亲属）的精神病发作年龄。方法：除了精神病发作的年龄外，我们还研究了精神分裂症的危险因素，包括产科并发症，冬季或春季出生，行为异常或运动和言语发育迟缓，暴露于不良生活事件和使用药物的人群100位患者（45位女性，55位男性）的平均年龄（±标准差）为35.15±13.21。结果：非家族性精神分裂症患者的出生并发症和大麻滥用是精神分裂症较早发作的预测因素。尚未发现家族性精神分裂症发病年龄较早的环境危险因素。结论：精神分裂症的某些环境危险因素似乎对非家族性精神分裂症的精神病发作年龄有影响，似乎对家族性精神分裂症没有影响。

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