Amyloidosis: The Newer Discovered ALECT2 Associated with der7q add(7)

Amrita Chakrabarti; Priyanka Samal; Joydeep Chakrabartty

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Amyloidosis: The Newer Discovered ALECT2 Associated with der7q add(7)

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Amyloidosis is characterized by pathological deposition of abnormal protein aggregates in various tissues, AL protein being the commonest. ALECT 2 is the newest protein described, having a predisposition to affect the kidneys, sometimes the liver and rarely other organs. We present a case of renal amyloid ALECT 2 due to leucocyte cell derived chemotaxin 2, a novel amyloidogenic protein. The patient presented with mild proteinuria, scattered plasma cells on bone marrow examination and altered kappa/lambda ratio with associated cytogenetic abnormality of der7q add(7). It is essential to correctly type this protein and differentiate it from AL during diagnosis for appropriate and effective clinical management.

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《journal of clinical and diagnostic research》 |2016年第9期|4-5|共2页
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Amrita Chakrabarti; Priyanka Samal; Joydeep Chakrabartty;
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Amyloidosis: The Newer Discovered ALECT2 Associated with der7q add(7)

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