首页> 外文期刊>Nucleic Acids Research >Mitochondrial RNAs of myxomycetes terminate with non-encoded 3' poly(U) tails.
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Mitochondrial RNAs of myxomycetes terminate with non-encoded 3' poly(U) tails.

机译:粘菌丝体的线粒体RNA以未编码的3'poly(U)尾巴终止。

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摘要

We examined the 3' ends of edited RNAs from the myxomycetes Stemonitis flavogenita and Physarum polycephalum using a modified anchor PCR approach. Surprisingly, we found that poly(A) tails are missing from the cytochrome c oxidase subunit 1 mRNA (coI) from both species and the cytochrome c oxidase subunit 3 mRNA (cox3) from P. polycephalum. Instead, non-encoded poly(U) tails of varying length were discovered at the 3' ends of these transcripts. These are the first described examples of 3' poly(U) tails on mature mRNAs in any system.
机译:我们使用改良的锚定PCR方法检查了粘菌丝状黄萎病菌和多头Physarum polycephalum的编辑RNA的3'端。令人惊讶的是,我们发现两种物种的细胞色素C氧化酶亚基1 mRNA(coI)和多头疟原虫的细胞色素C氧化酶亚基3 mRNA(cox3)都缺少poly(A)尾巴。而是在这些成绩单的3'末端发现了不同长度的未编码poly(U)尾巴。这些是在任何系统中成熟mRNA上3'poly(U)尾巴的第一个描述示例。

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