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SUNrises on the International Plant Nucleus Consortium: SEB Salzburg 2012

机译:国际植物核联合会上的日出:SEB萨尔茨堡2012

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The nuclear periphery is a dynamic, structured environment, whose precise functions are essential for global processes- from nuclear, to cellular, to organismal. Its main components- the nuclear envelope (NE) with inner and outer nuclear membranes (INM and ONM), nuclear pore complexes (NPC), associated cytoskeletal and nucleoskeletal components as well as chromatin are conserved across eukaryotes (Fig. 1). In metazoans in particular, the structure and functions of nuclear periphery components are intensely researched partly because of their involvement in various human diseases. While far less is known about these in plants, the last few years have seen a significant increase in research activity in this area. Plant biologists are not only catching up with the animal field, but recent findings are pushing our advances in this field globally. In recognition of this developing field, the Annual Society of Experimental Biology Meeting in Salzburg kindly hosted a session co-organized by Katja Graumann and David E. Evans (Oxford Brookes University) highlighting new insights into plant nuclear envelope proteins and their interactions. This session brought together leading researchers with expertise in topics such as epigenetics, meiosis, nuclear pore structure and functions, nucleoskeleton and nuclear envelope composition. An open and friendly exchange of ideas was fundamental to the success of the meeting, which resulted in founding the International Plant Nucleus Consortium. This review highlights new developments in plant nuclear envelope research presented at the conference and their importance for the wider understanding of metazoan, yeast and plant nuclear envelope functions and properties.
机译:核外围是一个动态,结构化的环境,其精确功能对于从核到细胞到有机的全球过程至关重要。它的主要成分-带有内部和外部核膜(INM和ONM)的核膜(NE),核孔复合物(NPC),相关的细胞骨架和核骨架成分以及染色质在整个真核生物中都是保守的(图1)。特别是在后生动物中,人们对核外围组件的结构和功能进行了深入研究,部分原因是它们参与了各种人类疾病。尽管对植物中这些物质的了解还很少,但是最近几年该领域的研究活动显着增加。植物生物学家不仅在追赶动物领域,而且最近的发现也在全球推动我们在该领域的进步。为了认识到这一发展领域,萨尔茨堡年度实验生物学学会年会由牛津布鲁克斯大学的Katja Graumann和David E. Evans共同组织了一次会议,重点介绍了对植物核被膜蛋白及其相互作用的新见解。这次会议汇集了在表观遗传学,减数分裂,核孔结构和功能,核骨架和核被膜组成等方面具有专长的领先研究人员。公开和友好的思想交流是会议成功的基础,会议的成功就是建立了国际植物核联合会。这篇综述着重介绍了会议上提出的植物核被膜研究的新发展及其对后生动物,酵母和植物核被膜功能和特性的更广泛理解的重要性。

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