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Effects of a nutritional intervention on body composition, clinical status, and quality of life in patients with heart failure.

机译：营养干预对心力衰竭患者的身体成分，临床状态和生活质量的影响。

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OBJECTIVES: We assessed the effects of a nutritional intervention on clinical and nutritional status and quality of life in patients with heart failure. METHODS: Sixty-five patients with heart failure were assigned to one of two groups: the intervention group (IG; n = 30) received a sodium-restricted diet (2000 to 2400 mg/d) with restriction of total fluids to 1.5 L/d, and the control group (CG; n = 35) received traditional medical treatment and general nutritional recommendations. Anthropometric, body composition, physical activity, dietary, metabolic, clinical, and quality of life assessments were performed in all patients at baseline and 6 mo later. RESULTS: At the end of the study, kilocalories, macronutrients, and fluid intakes were significant lower in the IG than in the CG. Urinary excretion of sodium decreased significantly in the IG and increased in the CG (-7.9% versus 29.4%, P < 0.05). IG patients had significantly less frequent edema (37% versus 7.4%, P = 0.008) and fatigue (59.3% versus 25.9%, P = 0.012) at 6 mo than at baseline; in addition, functional class improved significantly, and no changes were observed in the CG. Extracellular water decreased -1.1 +/- 3.7% in the IG and increased 1.4 +/- 4.5% in the CG (P = 0.03). Physical activity increased 2.5% +/- 7.4% in the IG and decreased -3.1 +/- 12.0 in the CG (P < 0.05). The IG had a greater increase in total quality of life compared with the CG (19.3% versus 3.2%, P = 0.02). CONCLUSIONS: In this study, the beneficial effect of a supervised nutritional intervention was proved as part of a non-pharmacologic treatment of patients with heart failure, with improvements in clinical status and quality of life.
机译：目的：我们评估了营养干预对心力衰竭患者临床和营养状况以及生活质量的影响。方法：65例心力衰竭患者被分为两组之一：干预组（IG; n = 30）接受钠限制饮食（2000至2400 mg / d），总液体限制为1.5 L / d，对照组（CG; n = 35）接受传统药物治疗和一般营养推荐。在基线及以后6个月，对所有患者进行人体测量，身体组成，身体活动，饮食，代谢，临床和生活质量评估。结果：在研究结束时，IG的卡路里，大量营养素和液体摄入量显着低于CG。 IG中尿钠的排泄显着降低，而CG中尿钠的排泄显着增加（-7.9％对29.4％，P <0.05）。与基线相比，IG患者在6个月时的水肿程度（37％比7.4％，P = 0.008）和疲劳程度（59.3％vs 25.9％，P = 0.012）显着减少。此外，功能类别明显改善，并且在CG中未观察到变化。细胞外水在IG中下降了-1.1 +/- 3.7％，在CG中上升了1.4 +/- 4.5％（P = 0.03）。体力活动在IG中增加2.5％+/- 7.4％，在CG中减少-3.1 +/- 12.0（P <0.05）。与CG相比，IG的总生活质量有更大的提高（19.3％对3.2％，P = 0.02）。结论：在这项研究中，有监督的营养干预措施的有益效果被证明是对心力衰竭患者进行非药物治疗的一部分，改善了临床状况和生活质量。

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