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首页> 外文期刊>Nursing philosophy: an international journal for healthcare professionals >Invisible economics of nursing: Analysis of a hospital bill through a Foucauldian perspective
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Invisible economics of nursing: Analysis of a hospital bill through a Foucauldian perspective

机译：无形的护理经济学：从福柯的角度分析医院账单

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Few studies are available that compare PBSC and BM from unrelated donors, especially in adult high-risk ALL. To determine which graft source is superior in adult high-risk ALL, we analyzed the long-term outcomes of 106 consecutive transplants from 8/8-matched or 7/8-matched unrelated donors (38 PBSC vs 68 BM). All patients received a uniform strategy of pre-transplant therapy, myeloablative conditioning and GVHD prophylaxis. At 5 years, PBSC transplants showed higher incidence of chronic GVHD than did BM transplants (74.3% vs 46.7%, P=0.001). PBSC transplants showed outcomes comparable to those of BM transplants for relapse (23.7% vs 28.1%), non-relapse mortality (18.4% vs 25.0%), disease-free survival (57.9% vs 46.9%) and OS (57.9% vs 50.0%). In a separate comparison of outcomes between the two graft sources according to the presence of a Ph chromosome, no significant advantage of PBSC over BM was found in both subgroups of patients. Our data suggest that the outcomes of unrelated donor transplantation are similar between PBSC and BM in adult high-risk ALL. Whether PBSC should be the preferred graft source for a specific subgroup of adult ALL needs to be further investigated.
机译：很少有研究可以比较无关亲属的PBSC和BM，特别是在成人高危ALL中。为了确定在成人高危ALL中哪种移植物来源更好，我们分析了8/8匹配或7/8匹配无关供者的106次连续移植的长期结果（38 PBSC vs 68 BM）。所有患者均接受了统一的移植前治疗，骨髓消融调节和GVHD预防策略。在5年时，PBSC移植物显示出慢性GVHD的发生率高于BM移植物（分别为74.3％和46.7％，P = 0.001）。 PBSC移植的复发率（23.7％vs 28.1％），非复发死亡率（18.4％vs 25.0％），无病生存期（57.9％vs 46.9％）和OS（57.9％vs 50.0）的结果与BM移植相当％）。在根据Ph染色体的存在情况对两个移植物来源之间的结果进行单独比较时，在两个患者亚组中均未发现PBSC优于BM。我们的数据表明，在成人高危ALL中，PBSC和BM之间无关的供体移植的结果相似。 PBSC是否应作为成人ALL特定亚组的首选移植物来源需要进一步研究。

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