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首页> 外文期刊>Nutrition Research >Both human immunodeficiency virus-infected and human immunodeficiency virus-exposed, uninfected children living in Brazil, Argentina, and Mexico have similar rates of low concentrations of retinol, o-carotene, and vitamin E
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Both human immunodeficiency virus-infected and human immunodeficiency virus-exposed, uninfected children living in Brazil, Argentina, and Mexico have similar rates of low concentrations of retinol, o-carotene, and vitamin E

机译：生活在巴西，阿根廷和墨西哥的未感染人类免疫缺陷病毒的儿童和暴露于人类免疫缺陷病毒的儿童的视黄醇，邻胡萝卜素和维生素E的低浓度发生率相似

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Our objective was to describe the prevalence of low concentrations of retinol, beta-carotene, and vitamin E in a group of human immunodeficiency virus (HIV)-infected Latin American children and a comparison group of HIV-exposed, uninfected children. Our hypothesis was that the rates of low concentrations of these micronutrients would be higher in the HIV-infected group than those in the HIV-exposed, uninfected group. This was a cross-sectional substudy of a larger cohort study at clinical pediatric HIV centers in Latin America. Serum levels of micronutrients were measured in the first stored sample obtained after each child's first birthday by high-performance liquid chromatography. Low concentrations of retinol, beta-carotene, and vitamin E were defined as serum levels below 0.70, 0.35, and 18.0 mu mol/L, respectively. The Population for this analysis was 336 children (124 HIV-infected, 212 HIV-exposed, uninfected) aged I year or older to younger than 4 years. Rates of low concentrations were 74% for retinol, 27% for beta-carotene, and 89% for vitamin E. These rates were not affected by HIV status. Among the HIV-infected children, those treated with anti retrovirals were less likely to have retinol deficiency, but no other HIV-related factors correlated with micronutrient low serum levels. Low concentrations of retinol, beta-carotene, and vitamin E are very common in children exposed to HIV living in Brazil, Argentina, and Mexico, regardless of HIV-infection status
机译：我们的目的是描述一组低水平视黄醇，β-胡萝卜素和维生素E在感染了人类免疫缺陷病毒（HIV）的拉丁美洲儿童和未接触HIV的对照组中的患病率。我们的假设是，在受HIV感染的人群中，这些微量营养素的低浓度发生率要高于未受HIV感染的人群。这是在拉丁美洲的临床儿科HIV中心进行的一项较大队列研究的横断面研究。通过高效液相色谱法测量每个孩子的第一岁生日后获得的第一个储存样品中的微量营养素水平。低浓度的视黄醇，β-胡萝卜素和维生素E被定义为血清水平分别低于0.70、0.35和18.0μmol/ L。该分析的人群为336岁（1岁或4岁以下）的336名儿童（124名HIV感染者，212名HIV感染者，未感染）。视黄醇的低浓度比率为74％，β-胡萝卜素为27％，维生素E为89％。这些比率不受HIV状况的影响。在受HIV感染的儿童中，接受抗逆转录病毒治疗的儿童较少出现视黄醇缺乏症，但没有其他与HIV相关的因素与微量营养素低血清水平相关。低浓度的视黄醇，β-胡萝卜素和维生素E在生活在巴西，阿根廷和墨西哥的暴露于HIV的儿童中非常普遍，而与HIV感染状况无关

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