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首页> 外文期刊>Nutrition Reviews >The bone remodeling transient: interpreting interventions involving bone-related nutrients.
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The bone remodeling transient: interpreting interventions involving bone-related nutrients.

机译:骨骼重塑瞬态:解释涉及骨骼相关营养的干预措施。

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摘要

The bone remodeling transient is a temporary alteration in the balance between bone formation and bone resorption, brought about by any agency that affects bone remodeling. Ascertaining the steady state effect of an intervention requires factoring the component of the change due to the transient out of the total bony response. Since parathyroid hormone (PTH) is the principal regulator of the quantity of remodeling activity, and since calcium intake influences PTH secretion, it follows that altering calcium intake will always induce a remodeling transient. Worked examples from three published calcium intervention studies are presented, and the errors that can be made by ignoring the transient and simply measuring change in bone mass across treatment are described.
机译:骨骼重塑瞬态是骨骼形成和骨骼吸收之间平衡的暂时性变化,这是由任何影响骨骼重塑的因素引起的。确定干预措施的稳态效果需要将总瞬态响应之外的瞬变引起的变化因素考虑在内。由于甲状旁腺激素(PTH)是重塑活动量的主要调节剂,并且由于钙摄入量会影响PTH分泌,因此可以得出结论,改变钙摄入量总是会引起重塑短暂。介绍了三个已发表的钙干预研究的工作实例,并描述了通过忽略瞬态并简单地测量整个治疗过程中骨量变化而可能产生的错误。

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