Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

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Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

机译：淀粉样蛋白和神经退行性生物标志物状态与痴呆之间的转化率：一项基于人群的纵向队列研究

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Background In a 2014 cross-sectional analysis, we showed that amyloid and neurodegeneration biomarker states in participants with no clinical impairment varied greatly with age, suggesting dynamic within-person processes. In this longitudinal study, we aimed to estimate rates of transition from a less to a more abnormal biomarker state by age in individuals without dementia, as well as to assess rates of transition to dementia from an abnormal state.

机译：背景在2014年的一项横断面分析中，我们发现没有临床障碍的参与者的淀粉样蛋白和神经退行性生物标志物状态随年龄变化很大，表明人体内动态过程。在这项纵向研究中，我们旨在评估没有痴呆症的个体按年龄从较低的生物标志物状态转变为更加异常的生物标志物的比率，以及评估从异常状态转变为痴呆症的比率。

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《Lancet Neurology》 |2016年第1期|共9页
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中图分类神经病学与精神病学;
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1. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study [J] . Lancet Neurology . 2016,第1期

机译：淀粉样蛋白和神经退行性生物标志物状态与痴呆之间的转化率：一项基于人群的纵向队列研究
2. Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study [J] . Sabrina Schilling, Christophe Tzourio, A?cha Soumaré, PLoS Medicine . 2017,第3期

机译：3C研究中血浆脂质与痴呆和痴呆亚型之间的差异性关联：一项基于人群的纵向前瞻性队列研究
3. Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study [J] . Sabrina Schilling, Christophe Tzourio, A?cha Soumaré, PLoS Medicine . 2017,第3期

机译：3C研究中血浆脂质与痴呆和痴呆亚型之间的差异性关联：一项基于人群的纵向前瞻性队列研究
4. Urban Green Space and the Risk of Dementia: A Population-Based Cohort Study [C] . Lauren Paul, Perry Hystad, Rick Burnett, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：城市绿地与痴呆症的风险：一项基于人群的队列研究
5. Integrated Structural and Functional Biomarkers for Neurodegeneration. [D] . Kandel, Benjamin. 2017

机译：用于神经变性的整合结构和功能生物标记。
6. Rates of transition between amyloid and neurodegeneration biomarker states and to dementia among non-demented individuals: a population-based cohort study [O] . Clifford R. Jack Jr., Terry M. Therneau, Heather J. Wiste, -1

机译：淀粉样蛋白和神经退行性生物标志物状态之间的转化率以及非痴呆个体向痴呆的转化率：一项基于人群的队列研究
7. Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study. [O] . Sabrina Schilling, Christophe Tzourio, Aïcha Soumaré, 2017

机译：在3C研究中，血浆脂质与痴呆和痴呆亚型的差异关联：纵向，基于人群的前瞻性队列研究。

Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

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