Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial

Azzopardi Denis; Robertson Nicola J.; Bainbridge Alan; Cady Ernest; Charles-Edwards Geoffrey; Deierl Aniko; Fagiolo Gianlorenzo; Franks Nicholas P.; Griffiths James; Hajnal Joseph; Juszczak Edmund; Kapetanakis Basil; Linsell Louise; Maze Mervyn; Omar Omar; Strohm Brenda; Tusor Nora; Edwards A. David

首页> 外文期刊>Lancet Neurology >Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial

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Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial

机译：出生后6小时内的中度低温加上吸入的氙气与出生后窒息后单独进行中度低温（TOBY-Xe）：概念验证，开放标签，随机对照试验

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Background Moderate cooling after birth asphyxia is associated with substantial reductions in death and disability, but additional therapies might provide further benefit. We assessed whether the addition of xenon gas, a promising novel therapy, after the initiation of hypothermia for birth asphyxia would result in further improvement.

机译：背景技术出生后窒息后的适度降温与死亡和残疾的显着减少有关，但是其他疗法可能会带来更多好处。我们评估了在为出生婴儿窒息的体温过低开始后，添加氙气（一种有前途的新疗法）是否会导致进一步的改善。

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《Lancet Neurology》 |2016年第2期|共9页
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Azzopardi Denis; Robertson Nicola J.; Bainbridge Alan; Cady Ernest; Charles-Edwards Geoffrey; Deierl Aniko; Fagiolo Gianlorenzo; Franks Nicholas P.; Griffiths James; Hajnal Joseph; Juszczak Edmund; Kapetanakis Basil; Linsell Louise; Maze Mervyn; Omar Omar; Strohm Brenda; Tusor Nora; Edwards A. David;
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正文语种 eng
中图分类神经病学与精神病学;
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1. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial [J] . Azzopardi Denis, Robertson Nicola J., Bainbridge Alan, Lancet Neurology . 2016,第2期

机译：出生后6小时内的中度低温加上吸入的氙气与出生后窒息后单独进行中度低温（TOBY-Xe）：概念验证，开放标签，随机对照试验
2. Prospective qualification of early cerebral biomarkers in a randomised trial of treatment with xenon combined with moderate hypothermia after birth asphyxia [J] . Denis Azzopardi, Andrew T. Chew, Aniko Deierl, EBioMedicine . 2019,第6期

机译：随机试验在氙气治疗随机试验中的早期脑生物标志物的预期鉴定与窒息后中等体温过低
3. Therapeutic hypothermia for birth asphyxia in low-resource settings: a pilot randomised controlled trial. [J] . Robertson NJ, Nakakeeto M, Hagmann C, The Lancet . 2008,第9641期

机译：资源贫乏地区出生性窒息的低温治疗：一项随机对照试验。
4. Neuroprotection with Hypothermia Following Birth Asphyxia [C] . European Congress of Perinatal Medicine . 2006

机译：厌恶后脱脂后的耐低温神经保护症
5. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept open-label randomised controlled trial [O] . Denis Azzopardi, Nicola J Robertson, Alan Bainbridge, -1

机译：出生后6小时内的中等体温加上吸入的氙气与出生后窒息后单独进行中等体温的窒息（TOBY-Xe）：概念验证开放标签随机对照试验
6. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe):a proof-of-concept, open-label, randomised controlled trial [O] . Azzopardi, Denis, Robertson, Nicola J, Bainbridge, Alan, 2016

机译：出生后6小时内的中度低温加上氙气吸入与出生后窒息后单独进行中度低温（TOBY-Xe）：概念验证，开放标签，随机对照试验

Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial

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