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首页> 外文期刊>Cell motility and the cytoskeleton >Evidence for a sliding-resistance at the tip of the trypanosome flagellum.
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Evidence for a sliding-resistance at the tip of the trypanosome flagellum.

机译：锥虫鞭毛尖端有滑动阻力的证据。

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摘要

Motility in trypanosomes is achieved through the undulating behaviour of a single "9 + 2" flagellum; normally the flagellar waves begin at the flagellar tip and propagate towards the base. For flagella in general, however, propagation is from base-to-tip and it is believed that bend formation, and sustained regular oscillation, depend upon a localised resistance to inter-doublet sliding - which is normally conferred by structures at the flagellar base, typically the basal body. We therefore predicted that in trypanosomes there must be a resistive structure at the flagellar tip. Electron micrographs of Crithidia deanei, Herpetomonas megaseliae, Trypanosoma brucei and Leishmania major have confirmed that such attachments are present. Thus, it can be assumed that in trypanosomes microtubule sliding at the flagellar tip is resisted sufficiently to permit bend formation.
机译：锥虫的运动性是通过单个“ 9 + 2”鞭毛的起伏行为实现的。通常，鞭毛波从鞭毛尖端开始并向基部传播。但是，一般而言，对于鞭毛而言，传播是从基部到尖端，并且据信弯曲形成和持续的规则振荡取决于对双联体间滑动的局部抵抗力，这通常是由鞭毛基部的结构赋予的，通常是基体。因此，我们预测锥虫体内的鞭毛尖端必须具有抗性结构。肉毒杆菌，巨大疱疹，布鲁氏锥虫和大利什曼原虫的电子显微照片已证实存在这种附件。因此，可以认为在锥虫中，鞭毛尖端的微管滑动受到了足够的抵抗，以允许弯曲形成。

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