...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Laboratory Animal Science >EFFECTS OF ANESTHESIA AND OPEN-THORAX SURGERY ON CORONARY VASCULAR RESERVE IN SWINE
【24h】

EFFECTS OF ANESTHESIA AND OPEN-THORAX SURGERY ON CORONARY VASCULAR RESERVE IN SWINE

机译：麻醉和开胸手术对猪冠状动脉血管储备的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The coronary reactive hyperemic response was examined in seven pigs under anesthetized and conscious conditions, (i.e., 5 days and 3 and 5 weeks after surgery), Tygon catheters were inserted in the descending aorta of five pigs; transonic flow probes and hydraulic occluders were placed on the left cranial descending and/or left circumflex coronary arteries, Two pigs underwent long-term implantation of similar instruments, The coronary reactive hyperemic response, expressed as repayment of flow deficit, was induced by brief complete coronary artery occlusion for 15 sec, Baseline mean arterial pressure, heart rate, and coronary blood flow were similar in the anesthetized and conscious pigs, There was also no significant difference in repayment of flow deficit between the anesthetized and conscious pips 5 days after surgery, The repayment of flow deficit (709 +/- 144%) in conscious pigs 5 days after surgery tended to be greater, but was not statistically significant from that observed in the anesthetized pigs (510 +/- 79%), However, at 3 and 5 weeks after surgery, the reactive hyperemic flow and the repayment of flow deficit were numerically greater than those values observed in anesthetized pigs, The difference in reactive hyperemic flow between conscious and anesthetized pigs was statistically significant at week 3, The difference in repayment of flow deficit between conscious and anesthetized pigs was statistically significant at week 5, These results suggest that anesthesia, as well as recent surgery, attenuates coronary vascular reserve, The major factor in the attenuation of coronary reserve appears to be recent surgical manipulation, because repayment of flow deficit was still depressed in conscious pigs during the early phase of recovery from surgery.
机译：在麻醉和清醒条件下（即手术后第5天以及第3和5周）检查了7头猪的冠状动脉反应性充血反应，将Tygon导管插入5头猪的降主动脉中;在左颅降支和/或左回旋支冠状动脉上放置了跨音速血流探头和液压闭塞器，对两只猪进行了长期植入类似器械的治疗，短暂的完全诱发了冠状动脉反应性充血反应，表现为血流不足的偿还。麻醉和清醒猪的冠状动脉阻塞15秒，基线平均动脉压，心率和冠状动脉血流量相似，术后5天麻醉和清醒点之间的血流不足偿还率也无显着差异，术后5天清醒的猪的血流不足的补偿率（709 +/- 144％）往往更高，但与麻醉猪的（510 +/- 79％）相比，无统计学意义，但是在第3天术后5周，反应性充血流量和血流不足的偿还率明显高于麻醉猪的值。在第3周时，清醒和麻醉猪之间的反应性充血流量在统计学上是显着的;在第5周，清醒和麻醉猪之间的流量不足的偿还差异在统计学上是显着的。这些结果表明，麻醉以及最近的手术减弱了冠状血管储备，减少冠状动脉储备的主要因素似乎是最近进行的外科手术，因为清醒的猪在手术恢复的早期仍无法减少流量不足的偿还。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号