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Animal models of Helicobacter infection

机译：幽门螺杆菌感染的动物模型

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The Helicobocter genus was named only about 10 years ago to group a number of already described bacteria that did' not quite fit the genus in which they had been classified. For example, Helicobocter pylori, which had been named successively Campylobacter pyloridis, then Campylobacter pylori,was different from the other members of the Campylobacter genus, and it was the first to be placed in this genus, while being renamed accordingly. During the past decade, H. pylori has become recognized as one of the most common human pathogens, colonizing the gastric mucosa of almost all individuals exposed to poor hygienic conditions from childhood. It also is often found, albeit with a lower frequency, in groups of higher socioeconomic status. H. pylori causes chronic-active gastritis and is a major factor in tile pathogenesis of duodenal ulcers and, to a lesser extent, of gastric ulcers. In addition, the presence of this bacterium is now recognized as a risk factor for gastric adenocarcinoma and lymphoma. Nevertheless, most infections appear to be without clinical consequences. Other organisms now classified in the Helicobacter genus have been described both in animals and in humans since the end of the 19th century.
机译：Helicobocter属仅在大约十年前才被命名，以将许多已经描述的细菌分类为非常不适合的细菌。例如，幽门螺旋杆菌（Helicobocter pylori）先后被命名为幽门弯曲杆菌（Campylobacter pyloridis），然后被命名为幽门弯曲杆菌（Campylobacter pylori），它不同于弯曲杆菌属的其他成员，它是第一个被置于该弯曲杆菌属中的，并因此而被重命名。在过去的十年中，幽门螺杆菌已被公认为是最常见的人类病原体之一，几乎覆盖了所有从童年以来就处于不良卫生条件下的人的胃粘膜。尽管频率较低，但也经常在社会经济地位较高的人群中发现。幽门螺杆菌可引起慢性活动性胃炎，并且是十二指肠溃疡和胃溃疡（在较小程度上）发病的主要因素。另外，这种细菌的存在现在被认为是胃腺癌和淋巴瘤的危险因素。尽管如此，大多数感染似乎没有临床后果。自19世纪末以来，现在已在动物和人类中描述了现在归类为幽门螺杆菌属的其他生物。

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