Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin.

Katragkou A; Roilides E

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Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin.

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Acinetobacter baumannii may cause severe central nervous system (CNS) infections, such as meningitis and ventriculitis, especially in patients undergoing neurosurgical procedures or head trauma. Mortality ranges from 20 to 27 in different case series (3). Carbapenems have been considered the treatment of choice for severe infections. However, increasing numbers of carbapenem-resistant Acinetobacter isolates have been reported worldwide, dramatically reducing the existing therapeutic options (1).Over the past 30 years, colistin use has been limited due to concerns regarding its! toxicity along with the development of newer antibiotics with better safety profiles (5, 7). However, the increasing incidence of multidrug-resistant A baumannii in addition to a lack of new antimicrobial agents has reawakened interest in the utilization of colistin due to its good activity against this organism (7).

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《Journal of Clinical Microbiology》 |2005年第9期|4916-4917|共2页
作者
Katragkou A; Roilides E;
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作者单位

Korea Adv Inst Sci & Technol, Ctr Nanospin Spintron Mat, Taejon 305701, South Korea;

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原文格式 PDF
正文语种英语
中图分类医学微生物学（病原细菌学、病原微生物学）;
关键词
Acinetobacter Infections; Acinetobacter baumannii; Anti-Bacterial Agents; 不动杆菌感染; 粘菌素;

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2. Letter to the Editor: New Treatment Options of Blood Stream Infections Caused by Multidrug-Resistant Acinetobacter baumannii in Some Libyan Patients [J] . Alhussain A. Alawami, Houwayda Al Haji, Mohammed I.K. HamiedChedly ChouchaniAllaaeddin A. El Salabi Microbial drug resistance: MDR : Mechanisms, epidemiology, and disease . 2022,第1期

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3. Safety and efficacy of intravenous colistin use for the treatment of nosocomial multidrug-resistant Acinetobacter baumannii infections in a pediatric intensive care unit [J] . Isguder Rana, Agin Hasan, Ceylan GokhanBayram NuriDevrim Ilker American Journal of Infection Control . 2016,第6期

机译：Safety and efficacy of intravenous colistin use for the treatment of nosocomial multidrug-resistant Acinetobacter baumannii infections in a pediatric intensive care unit
4. Paracoccidioidomicose do sistema nervoso central: relato de caso Paracoccidioidomycosis of the central nervous system: case report [O] . CARLOS EDUARDO AMARAL PEREIRA DA SILVA, ANDERSON FINOTTI CORDEIRO, ANGELA MARIA GOLLNER, 2000

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Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin.

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