Possible role of endogenous growth inhibitors in regeneration of organs: searching for new approaches.

Giorgobiani N; Dzidziguri D; Rukhadze M; Rusishvili L; Tumanishvili G

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Possible role of endogenous growth inhibitors in regeneration of organs: searching for new approaches.

机译：内源性生长抑制剂在器官再生中的可能作用：寻找新方法。

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A hydrophilic protein component (12-17 kDa) of the thermostable protein complex (TSPC) of different organs (heart, liver, kidney, brain) of adult white rats has been identified using hydrophobic interaction chromatography (HIC). Chromatograms and spectra of the myocardial hydrophilic component of different animals (snail, pigeon, rat, pig) detected within the UV region (190-360 nm) have shown that in different organs of the same animal species as well as in the same organ (e.g. heart) of different species, TSPC contains identical hydrophilic components, i.e. there is clearly a phylogenetically conserved group of thermostable proteins that regulates proliferation processes.

机译：已使用疏水相互作用色谱法（HIC）鉴定了成年白鼠不同器官（心脏，肝脏，肾脏，大脑）的热稳定蛋白复合物（TSPC）的亲水蛋白成分（12-17 kDa）。在紫外线区域（190-360 nm）内检测到的不同动物（蜗牛，鸽子，大鼠，猪）的心肌亲水成分的色谱图和光谱图表明，在同一动物物种的不同器官中以及在同一器官中， TSPC包含相同种类的亲水成分，也就是说，显然存在一个系统发育保守的热稳定蛋白，可调节增殖过程。

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《Cell biology international.》 |2005年第12期|共3页
作者
Giorgobiani N; Dzidziguri D; Rukhadze M; Rusishvili L; Tumanishvili G;
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正文语种 eng
中图分类细胞生物学;
关键词
Growth Inhibitors; Hydrophobicity; Myocardium; 生长抑制物; 心肌;

机译：Growth Inhibitors;Hydrophobicity;Myocardium;生长抑制物;心肌;

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1. 花叶千年木单个生殖器官和营养器官的体外直接再生的控制--单个器官直接再生的规律性 [J] . 陆文樑植物学报（英文版） . 2003,第012期
2. Possible role of endogenous growth inhibitors in regeneration of organs: searching for new approaches. [J] . Giorgobiani N, Dzidziguri D, Rukhadze M, Cell biology international. . 2005,第12期

机译：内源性生长抑制剂在器官再生中的可能作用：寻找新方法。
3. Potential roles of HDAC inhibitors in mitigating ischemia-induced brain damage and facilitating endogenous regeneration and recovery [J] . FesslerE.B., ChibaneF.L., WangZ., Current pharmaceutical design . 2013,第28期

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机译：调查钾通道在头发生长中的作用。研究证实了毛囊中存在几个ATP敏感性钾（K + ATP）通道，并使用分子生物学，细胞培养，器官培养和蛋白质组学方法探索了它们的作用机理。

Possible role of endogenous growth inhibitors in regeneration of organs: searching for new approaches.

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