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EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water by Direct Aqueous Injection with the Agilent 6460 Triple Quadrupole LC/MS System

机译:EPA方法538:使用Agilent 6460三重四极杆LC / MS系统通过直接水进样确定饮用水中的选定有机污染物

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摘要

A new method from the U.S. EPA (538) on 11 selected organic contaminants in drinking water by direct aqueous injection liquid chromatography/mass spectrometry/mass spectrometry (LC/MS/MS) has been developed using ultra-high-performance liquid chromatography (UHPLC) and the Agilent Model 6460 triple quadrupole LC/MS System. One advantage of the EPA method is that solid phase extraction (SPE) is no longer needed for sample preparation. This means that the analysis time is reduced by at least half.Furthermore, run time was cut by almost two-thirds by the use of UHPLC.The method provided excellent linearity (R220.9999) for all analytes, with limits of detection from 1 to 500 ng/L.
机译:使用超高效液相色谱(UHPLC)开发了一种新方法,该方法来自美国EPA(538)通过直接水相进样液相色谱/质谱/质谱(LC / MS / MS)对饮用水中的11种选定有机污染物进行了开发)和安捷伦6460型三重四极杆LC / MS系统。 EPA方法的一个优势是样品制备不再需要固相萃取(SPE)。这意味着分析时间至少减少了一半,而且使用UHPLC将运行时间缩短了近三分之二,该方法为所有分析物提供了出色的线性(R220.9999),检出限从1到500 ng / L。

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