Quantification of Individual Mass Transfer Phenomena in Liquid Chromatography for Further Improvement of Column Efficiency

Gritti Fabrice

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Quantification of Individual Mass Transfer Phenomena in Liquid Chromatography for Further Improvement of Column Efficiency

机译：液相色谱中单个传质现象的定量分析，以进一步提高色谱柱效率

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This article reports on the physical phenomena that control column efficiency and on experimental protocols designed to accurately measure their contributions to band broadening of analytes during their passage from the injection to the detection device. The results of these protocols are analyzed, allowing for the accurate determination of the complete mass transfer mechanism in different separation modes and providing solutions and future directions to further improve the efficiency of liquid chromatography columns.

机译：本文报道了控制色谱柱效率的物理现象，以及旨在准确测量分析物从进样到检测装置通过过程中对分析物的谱带展宽做出贡献的实验规程。对这些协议的结果进行了分析，从而可以在不同的分离模式下准确确定完整的传质机理，并提供解决方案和未来的方向，以进一步提高液相色谱柱的效率。

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《LC GC North America》 |2015年第2suppla期|共13页
作者
Gritti Fabrice;
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正文语种 eng
中图分类分析化学;
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1. Quantification of Individual Mass Transfer Phenomena in Liquid Chromatography for Further Improvement of Column Efficiency [J] . Gritti Fabrice LC GC North America . 2015,第2Suppla期

机译：液相色谱中单个传质现象的定量分析，以进一步提高色谱柱效率
2. Parallel extraction columns and parallel analytical columns coupled with liquid chromatography/tandem mass spectrometry for on-line simultaneous quantification of a drug candidate and its six metabolites in dog plasma [J] . Xia YQ., Liu DQ., Vincent SH., Rapid Communications in Mass Spectrometry: RCM . 2001,第22期

机译：平行萃取柱和平行分析柱结合液相色谱/串联质谱法在线同时定量检测狗血浆中的候选药物及其六种代谢物
3. Quantification of eight benzodiazepines in human breastmilk and plasma by liquid-liquid extraction and liquid-chromatography tandem mass spectrometry: Application to evaluation of alprazolam transfer into breastmilk [J] . Furugen Ayako, Nishimura Ayako, Kobayashi Masaki, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2019,第期

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4. Heart-Cut Column Switching Liquid Chromatography and Tandem Mass Spectrometry for the Quantification of Psychosine in Mouse Brain [C] . Xuntian Jiang, Jacqui Hawkins, Mark Sands, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

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5. MASS TRANSFER EFFICIENCY OF SIEVE TRAY LIQUID-LIQUID EXTRACTION COLUMNS. [D] . ROCHA-URIBE, JOSE ANTONIO. 1984

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6. Targeted Precise Quantification of 12 Human Recombinant Uridine-Diphosphate Glucuronosyl Transferase 1A and 2B Isoforms Using Nano-Ultra-High-Performance Liquid Chromatography/Tandem Mass Spectrometry with Selected Reaction Monitoring [O] . John K. Fallon, Hendrik Neubert, Theunis C. Goosen, -1

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7. Quantification of eight benzodiazepines in human breastmilk and plasma by liquid-liquid extraction and liquid-chromatography tandem mass spectrometry: Application to evaluation of alprazolam transfer into breastmilk [O] . Ayako Furugen, Ayako Nishimura, Masaki Kobayashi, 2019

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Quantification of Individual Mass Transfer Phenomena in Liquid Chromatography for Further Improvement of Column Efficiency

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