Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development

JinM.; DuX.; ChenL.

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Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development

机译：软骨内骨发育过程中FGF与其他细胞因子信号通路之间的串扰

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FGF (fibroblast growth factor)/FGFR (FGF receptor) signalling plays an essential role in both endochondral and intramembranous bone development. FGF signalling pathways are important for the earliest stages of limb development and throughout skeletal development. The activity and the outcome of this signalling pathway during bone development are also influenced by many other intracellular and extracellular signals. In this review, we focus on the interplay between FGF signalling and other pathways, which is tightly regulated both spatially and temporally during endochondral skeletal development.

机译：FGF（成纤维细胞生长因子）/ FGFR（FGF受体）信号传导在软骨内和膜内骨发育中都起着至关重要的作用。 FGF信号通路对于肢体发育的最早阶段以及整个骨骼发育都很重要。骨骼发育过程中该信号通路的活性和结果也受许多其他细胞内和细胞外信号的影响。在这篇综述中，我们着眼于FGF信号传导与其他途径之间的相互作用，该途径在软骨内骨骼发育过程中在空间和时间上都受到严格调控。

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《Cell biology international.》 |2012年第8期|共6页
作者
JinM.; DuX.; ChenL.;
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正文语种 eng
中图分类细胞生物学;
关键词
Cross-talk; Endochondral bone development; Fgf; Fgfr; Signalling pathway;

机译：串扰;软骨内骨骼发育;Fgf;Fgfr;信号通路;

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1. 软骨发育过程中负调控Sox9基因表达机制研究进展 [J] . 刘庆珍, 吴尽, 邳晓盟, 农业科学与技术（英文版） . 2017,第006期
2. Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development [J] . JinM., DuX., ChenL. Cell biology international. . 2012,第8期

机译：软骨内骨发育过程中FGF与其他细胞因子信号通路之间的串扰
3. FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development. [J] . Kim HJ, Rice DP, Kettunen PJ, Development . 1998,第7期

机译：FGF，BMP和Shh介导的信号通路在颅缝线形态发生和颅骨发育的调控中。
4. Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling [J] . Lomeli R. Carpio, Elizabeth W. Bradley, Meghan E. McGee-Lawrence, Science Signaling . 2016,第440期

机译：组蛋白脱乙酰基酶3通过控制细胞因子信号传导和基质重塑来支持软骨内骨形成
5. Global phosphorylation profiling reveals pathways in cardio-protective signaling induced by Fibroblast Growth Factor 2 (FGF2) during Cardiac Ischemia/Reperfusion injury [C] . Aruna B. Wijeratne, Janet Manning, Jo El J. Schultz, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：全局磷酸化分析揭示了心脏缺血/再灌注损伤期间由成纤维细胞生长因子2（FGF2）引起的心脏保护信号传导的途径
6. Challenging the Dogma of Canonical BMP Signaling in the Absence of Smad4 during Endochondral Bone Formation [D] . Rigueur, Diana 2016

机译：在缺乏Smad4的软骨内骨形成过程中挑战典型的BMP信号的信条。
7. A Ser252Trp Mutation in Fibroblast Growth Factor Receptor 2 (FGFR2) Mimicking Human Apert Syndrome Reveals an Essential Role for FGF Signaling in the Regulation of Endochondral Bone Formation [O] . Peng Chen, Li Zhang, Tujun Weng, -1

机译：模仿人类阿普氏综合征的成纤维细胞生长因子受体2（FGFR2）中的Ser252Trp突变揭示了FGF信号传导在调节软骨内骨形成中的重要作用。
8. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease [O] . D. M. Ornitz 2002

机译：CofoChondrall和Intramermalaous骨骼发育中的FGF信号传导途径和人类遗传症

Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development

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