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首页> 外文期刊>Caries research >Lack of Effect of Chlorhexidine Varnish on Streptococcus mutans Transmission and Caries in Mothers and Children.
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Lack of Effect of Chlorhexidine Varnish on Streptococcus mutans Transmission and Caries in Mothers and Children.

机译：洗必泰清漆对变形链球菌的传播和母亲和儿童龋齿的影响不足。

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摘要

In a randomized clinical trial, we evaluated the effect of a 10% chlorhexidine varnish (Chlorzoin((R))) on the mother-child transmission of Streptococcus mutans and on subsequent caries experience. Chlorhexidine (n = 38) or a placebo varnish (n = 37) was applied to the dentitions of 75 mothers at a time when their first babies were about 6 months old (approximate time of first tooth emergence). Three more applications at weekly intervals and subsequent applications at 6-month intervals followed the initial application. The mother-child pairs were followed up until the child's fourth birthday. Maternal salivary S. mutans levels in the treatment group remained significantly lower (p < 0.05) compared to the control group up to 12 months after the initial application. However, this intervention did not significantly alter the S. mutans colonization in children or the caries increment in either the mother or the child.
机译：在一项随机临床试验中，我们评估了10％洗必泰清漆（Chlorzoin（R））对变形链球菌母婴传播以及随后龋病的影响。在75名母亲的第一个婴儿大约6个月大时（大约是第一次出牙的时间），将洗必泰（n = 38）或安慰剂清漆（n = 37）应用于牙列。首次申请之后，每周再进行三次申请，之后每六个月进行一次申请。对母子俩进行跟进直至孩子的四岁生日。在初次使用后的12个月内，治疗组的孕妇唾液变形链球菌水平仍显着低于对照组（p <0.05）。但是，这种干预并没有显着改变儿童变形链球菌的定殖或母亲或儿童的龋齿增加。

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