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首页> 外文期刊>Caries research >Plaque fluoride concentrations are dependent on plaque calcium concentrations.
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Plaque fluoride concentrations are dependent on plaque calcium concentrations.

机译：斑块氟化物的浓度取决于斑块钙的浓度。

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Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental plaque is related more to the [F] of the dentifrice used or to the plaque concentrations of calcium and magnesium. The subjects (n = 13) were adults and residents of a city served with fluoridated drinking water. After 1 week of using a fluoridated dentifrice (940 ppm) or a placebo dentifrice, whole saliva and plaque were collected 1.0 h and approximately 12 h after the last use of the dentifrices. The average salivary [F] after brushing with the F dentifrice was higher than after using the placebo. The average plaque [F] 1.0 h after brushing with the F dentifrice was higher than after using the placebo (p < 0.01), but the difference at 12 h was not significant. Plaque [Ca] and [F] were directly related under all experimental conditions (p = 0.0001). The relationships between plaque [Mg] and [F] were weaker and inconsistent. Based on these findings and reports in the literature it is concluded that, for persons whose drinking water is fluoridated, plaque [F] throughout much of the day is not significantly increased by the use of a fluoridated dentifrice. Instead they are directly related to plaque [Ca]. These findings offer at least a partial explanation for why fluoridated dentifrices and drinking water have similar cariostatic effects.
机译：尽管洁牙剂和含氟饮用水中的氟化物浓度（[F]）相差1000倍，但临床和流行病学研究表明，它们具有相似的抑癌作用。进行了这项双盲，交叉研究，以确定牙菌斑中的[F]与所用洁牙剂的[F]或钙和镁的牙斑浓度之间的关系是否更大。受试者（n = 13）是成年人，是城市居民，他们都饮用了氟化饮用水。在使用氟化洁齿剂（940 ppm）或安慰剂洁齿剂1周后，在最后一次使用洁牙剂后1.0 h和约12 h收集全部唾液和牙菌斑。用F洁牙剂刷牙后的平均唾液[F]高于使用安慰剂后的唾液[F]。用F洁牙剂刷牙后1.0 h的平均菌斑[F]高于使用安慰剂后的菌斑（p <0.01），但在12 h时的差异并不显着。在所有实验条件下，菌斑[Ca]和[F]直接相关（p = 0.0001）。斑块[Mg]和[F]之间的关系较弱且不一致。根据这些发现和文献报道，可以得出结论，对于饮用水中的氟化物，使用氟化洁牙剂在一天中的大部分时间中斑块[F]不会显着增加。相反，它们与斑块[Ca]直接相关。这些发现至少部分解释了为什么氟化牙粉和饮用水具有相似的抗癌作用。

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