Involvement of protein kinases on the process of erythrophagocytis by Entamoeba histolytica.

Batista Ed Ede J; De Souza W

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Involvement of protein kinases on the process of erythrophagocytis by Entamoeba histolytica.

机译：溶血性变形杆菌的蛋白激酶参与红噬细胞过程。

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Erythrophagocytic capacity of trophozoites of Entamoeba histolytica is considered a factor in the virulence of this pathogenic protozoan. We present evidence showing that such activity resembles the ingestion of microorganisms by highly differentiated phagocytic cells, such as macrophages. Previous treatment of the trophozoites with genistein or tyrphostin, inhibitors of tyrosine protein kinases, with staurosporine, a protein kinase C inhibitor, and wortmannin, a fungal metabolite that inhibits phosphoinositide 3-OH kinase, significantly inhibited their erythrophagocytic capacity.

机译：溶组织性变形杆菌的滋养体的红细胞吞噬能力被认为是这种致病性原生动物毒力的一个因素。我们提供的证据表明，这种活性类似于高分化吞噬细胞（例如巨噬细胞）对微生物的摄入。以前用染料木黄酮或酪氨酸酪氨酸抑制剂酪氨酸蛋白激酶，蛋白激酶C抑制剂星形孢菌素和抑制磷酸肌醇3-OH激酶的真菌代谢产物渥曼青霉素对滋养体的治疗显着地抑制了其促红细胞吞噬能力。

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《Cell biology international.》 |2004年第4期|共6页
作者
Batista Ed Ede J; De Souza W;
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正文语种 eng
中图分类细胞生物学;
关键词
Protein Kinases; Entamoeba histolytica; Involved; hydroxyl group; inhibitors; 蛋白激酶类; 内阿米巴; 溶组织;

机译：Protein Kinases;Entamoeba histolytica;Involved;hydroxyl group;inhibitors;蛋白激酶类;内阿米巴;溶组织;

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1. Involvement of protein kinases on the process of erythrophagocytis by Entamoeba histolytica. [J] . Batista Ed Ede J, De Souza W Cell biology international. . 2004,第4期

机译：溶血性变形杆菌的蛋白激酶参与红噬细胞过程。
2. Recent insights in Pre-mRNA 3'-end processing signals and proteins in the protozoan parasite Entamoeba histolytica. [J] . Lopez Camarillo C, Hernandez de la Cruz ON, Vivas JG, Infectious disorders drug targets . 2010,第4期

机译：原生动物寄生虫组织变形虫中的前mRNA 3'末端加工信号和蛋白质的最新见解。
3. Involvement of signaling through protein kinase C and phosphatidylinositol 3-kinase in the excystation and metacystic development of Entamoeba invadens. [J] . Makioka A, Kumagai M, Kobayashi S, Parasitology Research . 2003,第3期

机译：通过蛋白激酶C和磷脂酰肌醇3-激酶参与的信号转导和侵染Entamoeba的囊胚发展。
4. Activation of Mitogen-activated Protein Kinases and Protein Kinase B/akt Signaling By Oxidative Stress in Vascular Smooth Muscle Cells: involvement in Vascular Pathophysiology [C] . Ashok K. Srivastava, Nihar R. Pandey, Antoine Blanc International Society for Heart Research.Congress . 2004

机译：血管平滑肌细胞氧化应激激活丝裂剂活化蛋白激酶和蛋白激酶B / Akt信号传导：血管病理生理学中的参与
5. The structure, function and expression of the Gal/GalNac lectin and virulence proteins of Entamoeba histolytica. [D] . Beck, David L. 2005

机译：溶血变形杆菌的Gal / GalNac凝集素和毒力蛋白的结构，功能和表达。
6. Effects of gamma interferon on syntheses of DNA and proteins by Entamoeba histolytica. [O] . C Castellanos, C Ramos, L Ortiz-Ortiz 1989

机译：γ干扰素对溶组织变形杆菌的DNA和蛋白质合成的影响。
7. Heterotrimeric G-protein signaling is critical to pathogenic processes in Entamoeba histolytica. [O] . Dustin E Bosch, Adam J Kimple, Robin E Muller, 2012

机译：异源三聚体G蛋白信号传导对溶组织内阿米巴的致病过程至关重要。

Involvement of protein kinases on the process of erythrophagocytis by Entamoeba histolytica.

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