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Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle.

机译:钙在平滑肌中收缩因子增敏的调节机制。

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摘要

It is evident that smooth muscle contraction is regulated not only by the Ca2+/calmodulin/myosin light chain kinase system but also by modulation of Ca2+ sensitivity. Changes in free calmodulin concentrations, myosin light chain phosphorylation elicited by rho/rho-kinase, regulation of myosin phosphatase activity and thin filament-linked mechanisms are the possible mechanisms for regulation of Ca2+ sensitivity.
机译:显然,平滑肌收缩不仅受Ca2 + /钙调蛋白/肌球蛋白轻链激酶系统的调节,还受Ca2 +敏感性的调节。游离钙调蛋白浓度的变化,rho / rho激酶引起的肌球蛋白轻链磷酸化,肌球蛋白磷酸酶活性的调节和细丝连接机制是调节Ca2 +敏感性的可能机制。

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