Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

Colombo G; Agabio R; Diaz G; Lobina C; Reali R; Gessa GL

首页> 外文期刊>Life sciences >Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

【24h】

Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

机译：大麻拮抗剂SR 141716后的食欲抑制和体重减轻。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The effect of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight was assessed in adult, non-obese Wistar rats. The daily administration of SR 141716 (2.5 and 10 mg/kg; i.p.) reduced dose-dependently both food intake and body weight. Tolerance to the anorectic effect developed within 5 days; in contrast, body weight in SR 141716-treated rats remained markedly below that of vehicle-treated rats throughout the entire treatment period (14 days). The results suggest that brain cannabinoid receptors are involved in the regulation of appetite and body weight.

机译：在成年的非肥胖Wistar大鼠中评估了大麻素CB1受体拮抗剂SR 141716对食物摄入和体重的影响。每天服用SR 141716（2.5和10 mg / kg;腹腔注射）可剂量依赖性地减少食物摄入量和体重。 5天内出现对厌食症的耐受性;相反，在整个治疗期间（14天），SR 141716处理的大鼠的体重仍显着低于媒介物处理的大鼠。结果表明，脑大麻素受体参与食欲和体重的调节。

著录项

来源
《Life sciences》 |1998年第8期|共5页
作者
Colombo G; Agabio R; Diaz G; Lobina C; Reali R; Gessa GL;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生命的起源;生命科学总论;
关键词
Appetite; Appetite Depressants; Cannabinoids; Piperidines; Pyrazoles; Weight Loss; 食欲; 食欲抑制药; 大麻酚类; 哌啶类; 吡唑类; 体重减轻;

机译：Appetite;Appetite Depressants;Cannabinoids;Piperidines;Pyrazoles;Weight Loss;食欲;食欲抑制药;大麻酚类;哌啶类;吡唑类;体重减轻;

相似文献

外文文献
中文文献
专利

1. Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. [J] . Colombo G, Agabio R, Diaz G, Life sciences . 1998,第8期

机译：大麻拮抗剂SR 141716后的食欲抑制和体重减轻。
2. Boosting effect of morphine on alcohol drinking is suppressed not only by naloxone but also by the cannabinoid CB1 receptor antagonist, SR 141716. [J] . Vacca G, Serra S, Brunetti G, European Journal of Pharmacology: An International Journal . 2002,第1a2期

机译：吗啡对饮酒的促进作用不仅受到纳洛酮的抑制，而且受到大麻素CB1受体拮抗剂SR 141716的抑制。
3. Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities. [J] . Lin Y, Shia KS, Hsiao WC, Pharmacological research: The official journal of The Italian Pharmacological Society . 2010,第4期

机译：具有独特功能活性的大麻素CB1受体拮抗剂可双相抑制食欲。
4. Novel Engineered Particle Formulation for Inhaled PYY(3-36) And Demonstration of Appetite Suppression in a Mouse Model [C] . David T.Vodak, Daniel E. Dobry, Tracey Boyden, Annual meeting exposition of the Controlled Release Society . 2011

机译：吸入性PYY（3-36）的新型工程粒子配方和小鼠模型中食欲抑制的演示
5. Cannabinoid-induced immune suppression in mouse splenocytes involves both cannabinoid receptor-dependent and -independent mechanisms. [D] . Kaplan, Barbara Lee Faubert. 2001

机译：大麻素诱导的小鼠脾细胞免疫抑制涉及大麻素受体依赖性和非依赖性机制。
6. D1 and D2 antagonists reverse the effects of appetite suppressants on weight loss food intake locomotion and rebalance spiking inhibition in the rat NAc shell [O] . B. Kalyanasundar, Claudia I. Perez, Alvaro Luna, -1

机译：D1和D2拮抗剂可逆转食欲抑制剂对大鼠NAc外壳中体重减轻食物摄入运动和再平衡峰值抑制的影响
7. Intact Leptin Receptor Signalling is not Required for the Sustained Weight Loss and Appetite Suppression Induced by Roux-en-Y Gastric Bypass Surgery [O] . Mohammed K. Hankir, Laura Rotzinger, Arno Nordbeck, 2021

机译：Roux-Zh-Y胃旁路手术诱导的持续减肥和食欲抑制不需要完整的瘦素受体信号传导

Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

摘要

著录项

相似文献

相关主题

期刊订阅