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首页> 外文期刊>Life sciences >Pharmacological effects of Cimicifuga racemosa [Review]
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Pharmacological effects of Cimicifuga racemosa [Review]

机译：消灭地塞米松的药理作用[综述]

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摘要

Cimicifuga racemosa is widely employed to relieve menopause symptoms for its hormonal-like action. However, recent experimental studies have not found an estrogenic action by this plant. The purpose of this systematic review is to analyse all experimental studies (in vivo and in vitro) performed on C. racemosa to elucidate its mechanism of action. Animal and in vitro experiments on C. racemosa were identified through a computerised literature searches performed on Medline (PubMed), Embase, Amed, CISCOM and Cochrane Library databases. In addition, bibliographies of the articles thus located were scanned for further relevant publications and manufactures of commercial C. racemosa preparations were asked to contribute published and unpublished material. No language restrictions were imposed. A total of 15 animal and 15 in vitro studies on C. racemosa have been found. Their results suggest that C. racemosa possesses a central activity instead of a hormonal effect. Further biological and chemical investigations are required to define its mechanism of action and to identify the compounds responsible of its actions. (C) 2003 Elsevier Science Inc. All rights reserved. [References: 43]
机译：由于它具有荷尔蒙样的作用，因此，消灭Cimicifuga racemosa被广泛用于缓解更年期症状。但是，最近的实验研究尚未发现该植物具有雌激素作用。这篇系统综述的目的是分析对总状小球藻进行的所有实验研究（体内和体外），以阐明其作用机理。通过在Medline（PubMed），Embase，Amed，CISCOM和Cochrane Library数据库上进行的计算机文献检索，鉴定了消旋衣藻的动物和体外实验。此外，对由此找到的物品的书目进行了扫描，以寻找更多相关出版物，并要求商业消旋地衣藻制剂的生产商提供已发表和未发表的材料。没有语言限制。总共发现了15种动物和15种关于消旋衣藻的体外研究。他们的研究结果表明，总状花木具有中心活性而不是荷尔蒙作用。需要进一步的生物学和化学研究以定义其作用机理并鉴定引起其作用的化合物。 （C）2003 Elsevier Science Inc.保留所有权利。 [参考：43]

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