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首页> 外文期刊>Life sciences >A major health hazard: The metabolic syndrome.
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A major health hazard: The metabolic syndrome.

机译：主要健康危害：代谢综合症。

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The clustering of several metabolic and cardiovascular disease risk factors has been termed the metabolic syndrome. The metabolic syndrome seems to result from a collision between susceptible "thrifty genes" and a society characterized by an increased prevalence of obesity and a sedentary lifestyle. The typical patient is characterized by abdominal obesity, a varying degree of glucose intolerance, dyslipidemia and often hypertension. The components of the metabolic syndrome are associated with insulin resistance, disturbances of coagulation and fibrinolysis, endothelial dysfunction and elevated markers of sub-clinical inflammation. The current review focuses mainly on the new definitions of the syndrome, the results of recent epidemiological studies and the consequences of the metabolic syndrome as an important risk factor for cardiovascular disease, premature death and diabetes. The metabolic syndrome constitutes a major challenge for public health professionals in the field of preventive medicine since more than 40 million U.S. adults seem to be affected by the syndrome. Lifestyle changes could have a profound influence on the syndrome and its development.
机译：几种代谢和心血管疾病危险因素的聚集被称为代谢综合症。代谢综合症似乎是由于易感的“节俭基因”与以肥胖症和久坐的生活方式增加为特征的社会之间的碰撞而导致的。典型的患者的特征是腹部肥胖，不同程度的葡萄糖耐量异常，血脂异常以及通常为高血压。代谢综合征的成分与胰岛素抵抗，凝血和纤维蛋白溶解紊乱，内皮功能障碍以及亚临床炎症标志升高有关。目前的综述主要集中在综合征的新定义，近期流行病学研究的结果以及代谢综合征作为心血管疾病，过早死亡和糖尿病的重要危险因素的后果上。代谢综合症对预防医学领域的公共卫生专业人员构成了重大挑战，因为似乎有超过4000万美国成年人受到该综合症的影响。生活方式的改变可能对该综合症及其发展产生深远影响。

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