• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Life sciences >Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease
【24h】

Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease

机译：阿尔茨海默氏病和帕金森氏病患者脑脊液中总同型半胱氨酸浓度的增加

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We determined the concentrations of free homocysteine (HC) and total HC in the cerebrospinal fluid (CSF) of patients with Alzheimer's disease (AD) or Parkinson's disease (PD) in order to elucidate whether HC is related to the pathogenesis of these neurodegenerative diseases. The concentration of free HC did not differ significantly from that of the normal controls, while the concentration of total HC was significantly higher in the AD and PD patients (+31% in AD,+31% in PD; p < 0.05). These findings suggest that an increase of total HC concentration in the brain is commonly seen in patients with AD and PD, and this may be related to the pathogenesis of these two diseases. (c) 2005 Elsevier Inc. All rights reserved.
机译：我们确定患有阿尔茨海默氏病（AD）或帕金森氏病（PD）的患者的脑脊液（CSF）中游离高半胱氨酸（HC）和总HC的浓度，以阐明HC是否与这些神经退行性疾病的发病机制有关。游离HC的浓度与正常对照组相比无显着差异，而AD和PD患者的总HC浓度显着较高（AD + 31％，PD + 31％; p <0.05）。这些发现表明，AD和PD患者通常会发现大脑中总HC浓度增加，这可能与这两种疾病的发病机理有关。 （c）2005 Elsevier Inc.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号