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首页> 外文期刊>Life sciences >Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats.
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Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats.

机译：γ-谷氨酰胺对自发性高血压大鼠的降压作用。

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摘要

The effect of gamma-glutamylmethylamide(GMA), one of the components of green tea extract, on the blood pressure in spontaneously hypertensive rats (SHR) was investigated. The effect of glutamic acid and r-glutamylethylamide (theanine), which is structurally similar to GMA, was also examined. When SHR were injected with glutamic acid (2000mg/kg), the blood pressure was not altered. The same dose of theanine decreased it significantly. GMA administration to SHR reduced the blood pressure significantly, and its degree of hypotensive action was more effective than that by theanine administration.
机译：研究了绿茶提取物成分之一的γ-谷氨酰甲基酰胺（GMA）对自发性高血压大鼠（SHR）血压的影响。还检查了结构上类似于GMA的谷氨酸和r-谷氨酰乙酰胺（茶氨酸）的作用。当SHR注射谷氨酸（2000mg / kg）时，血压没有改变。相同剂量的茶氨酸可显着降低其剂量。 GMA给予SHR可以显着降低血压，其降压作用程度比茶氨酸给予更为有效。

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