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首页> 外文期刊>Life sciences >Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida fruits with health benefits.
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Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida fruits with health benefits.

机译：山茱alter，山茱tro，山茱ko和佛罗里达山茱fruits中的花色苷具有健康益处。

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The anthocyanins in native Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida were quantified by HPLC and characterized by spectroscopic methods. The analyses of C. alternifolia and C. controversa revealed that both contained , and , respectively. Similarly, C. florida and C. kousa showed identical anthocyanin profiles with major anthocyanins as and cyanidin 3-O-glucoside (6), respectively. The amount of anthocyanins , and in C. alternifolia and C. controversa were 8.21, 8.44 and 0.02 mg; and 7.74, 5.92, and 0.02 mg/g of fresh fruits, respectively. The anthocyanins and in C. kousa and C. florida were 0.02 and 0.16 mg; and 0.62 and 0.03 mg/g fresh fruits, respectively. Anthocyanins and were not studied earlier for their inhibition of lipid peroxidation, cyclooxygenase enzymes (COX-1 and COX-2), and tumor cell proliferation. At 50 microg/mL, anthocyanins and inhibited lipid peroxidation by 71% and 68%, respectively. Similarly, they inhibited COX-1 enzymes by 39% and 49% and COX-2 enzyme by 54% and 48%, respectively, at 100 microg/mL. Anthocyanin displayed 50% growth inhibition (IC(50)) at 21, 25, 50, 60, and 75 microg/mL, against HCT-116 (colon), MCF-7 (breast), NCI-H460 (lung), SF-268 (central nervous system CNS), and AGS (stomach) human tumor cell lines, respectively. Similarly, IC(50) values for anthocyanin were 38, 30, 76, 100, and 100 microg/mL against HCT-116, MCF-7, NCI H460, SF-268, and AGS, respectively. This is the first report of the quantification and biological activities of anthocyanins in C. alternifolia, C. kousa and C. florida in addition to the anthocyanins not previously quantified in C. controversa.
机译：通过HPLC对天然山茱Corn，山茱Corn，山茱ko和佛罗里达山茱中的花色苷进行定量，并通过光谱法对其进行表征。 C. alternifolia和C. controversa的分析显示，它们都分别包含和。类似地，佛罗里达C. kousa和C. kousa的花色苷分布图与主要花色苷和花青素3-O-葡萄糖苷（6）分别相同。花青素的含量分别为8.21、8.44和0.02 mg。分别为7.74、5.92和0.02 mg / g新鲜水果。花青素和C. kousa和C. florida的花青素分别为0.02和0.16 mg;新鲜水果分别为0.62和0.03 mg / g。花青素和花青素对脂质过氧化，环氧合酶（COX-1和COX-2）的抑制作用以及肿瘤细胞的增殖作用尚未得到研究。在50微克/毫升下，花青素和抑制脂质过氧化分别为71％和68％。同样，在100微克/毫升下，它们分别抑制了39％和49％的COX-1酶和54％和48％的COX-2酶。花青素对HCT-116（结肠），MCF-7（乳腺癌），NCI-H460（肺），SF分别显示21、25、50、60和75 microg / mL的50％生长抑制（IC（50）） -268（中枢神经系统CNS）和AGS（胃）人肿瘤细胞系。同样，针对HCT-116，MCF-7，NCI H460，SF-268和AGS的花色苷的IC（50）值分别为38、30、76、100和100微克/毫升。这是首次报道在互生念珠菌，C。kousa和佛罗里达梭菌中花色苷的定量和生物学活性，此外还没有以前在争议杯中定量的花青素。

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