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Effects of butylated hydroxytoluene (BHT) enriched diet on serum antioxidant activity in pre-and overtly diabetic nod mice.

机译:富含丁基化羟基甲苯(BHT)的饮食对糖尿病前和显性Nod小鼠血清抗氧化活性的影响。

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摘要

Preventive (antioxidant activity) and chain-breaking (total peroxyl radical-trapping parameter) antioxidants in the serum of controls and butylated hydroxytoluene (BHT)-diet enriched nonobese diabetic (NOD) and C57B16/J mice from 5 to 25 weeks of age are measured in this study. A significant decrease in the overall potency of both antioxidant types is demonstrated in NOD untreated controls but not in animals whose diet was BHT-enriched. Therefore, we show that alterations of the antioxidant status in NOD mice is efficaciously counteracted by BHT.
机译:5至25周龄的对照组和丁基化富含羟基甲苯(BHT)饮食的非肥胖糖尿病(NOD)和C57B16 / J小鼠的血清中具有预防性(抗氧化活性)和链断裂(总过氧自由基捕获参数)抗氧化剂在这项研究中测量。在未经NOD处理的对照组中证明了两种抗氧化剂类型的整体效能均显着降低,但在饮食中富含BHT的动物中却没有。因此,我们表明BHT有效地抵消了NOD小鼠中抗氧化剂状态的改变。

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