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首页> 外文期刊>Life sciences >The driving license examination as a stress model: effects on blood picture, serum cortisol and the production of interleukins in man.
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The driving license examination as a stress model: effects on blood picture, serum cortisol and the production of interleukins in man.

机译：驾驶执照考试是一种压力模型：对人的血像，血清皮质醇和白介素产生的影响。

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We have studied the following stress model: the tension caused by sitting for the theoretical part of the driving license examination. Volunteers were investigated twice, after their driving license examination and after a (stress-free) control session. The effects of the stress were investigated by studying the blood picture (differential counts), serum concentration of cortisol, and cytokine production in stimulated blood cells. Relationships between the subjective perception of stress and the physiological reaction were also investigated. This stress induced significant increase in the concentrations of cortisol and hemoglobin, and in the values of hematocrit and MCV, and in the lipopolysaccharide-induced release of IL-1beta and -6. The subjective feelings of irritability and wakefulness were also significantly higher after the exam. A significant relationship was found between the changes in the stimulated production of IL-1beta and irritability. The responsiveness to psychological stress might be influenced by the temporary mood of the subjects.
机译：我们研究了以下压力模型：坐在驾驶执照考试的理论部分所引起的张力。在对驾驶执照进行检查后以及（无压力）控制后，对志愿者进行了两次调查。通过研究血液图像（差异计数），皮质醇的血清浓度和刺激的血细胞中细胞因子的产生，研究了应激的影响。还研究了压力的主观感知与生理反应之间的关系。这种压力导致皮质醇和血红蛋白浓度，血细胞比容和MCV值以及脂多糖诱导的IL-1beta和-6释放显着增加。考试后，主观的烦躁和清醒感也明显更高。发现在刺激的IL-1β产生的变化与易怒之间存在显着的关系。对心理压力的反应能力可能受受试者的暂时情绪影响。

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