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首页> 外文期刊>Life sciences >A new clinical approach: Use of blood-derived stem cells (BDSCs) for superficial digital flexor tendon injuries in horses
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A new clinical approach: Use of blood-derived stem cells (BDSCs) for superficial digital flexor tendon injuries in horses

机译：一种新的临床方法：使用血源性干细胞（BDSC）治疗马的浅指屈肌腱损伤

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Aims: In this study, we present an innovative therapy using stem cells that were obtained from the peripheral blood of racehorses affected by uninduced superficial digital flexor tendon (SDFT) injuries. Main methods: Blood-derived stem cells (BDSCs) were generated from the blood samples of three horses in the presence of macrophage colony-stimulating factor (M-CSF). The racehorses received a single autologous BDSC treatment, which resulted in the successful repair of the tendons injuries. Key findings: The results demonstrated that the BDSCs injection into the damaged tendon stimulated the regeneration of normal tissue. Furthermore, a relationship may exist between the speed and the quality of new tissue formation and the welfare and management of the treated animals. Significance: This study demonstrates that stem cell technology offers new tools for tissue repair that in many cases is considered incurable, and provides additional evidence that BDScs injections increase the speed and quality of the regeneration process in different animal tissues.
机译：目的：在这项研究中，我们提出了一种创新的疗法，该疗法使用的干细胞是从受到未诱导的浅指屈肌腱（SDFT）损伤的赛马的外周血中获得的。主要方法：在存在巨噬细胞集落刺激因子（M-CSF）的情况下，从三匹马的血液样本中产生血源性干细胞（BDSC）。赛马接受了单一的自体BDSC治疗，从而成功修复了肌腱损伤。关键发现：结果表明，将BDSCs注入受损的肌腱可刺激正常组织的再生。此外，新组织形成的速度和质量与被治疗动物的福利和管理之间可能存在关系。启示：这项研究表明，干细胞技术为组织修复提供了新工具，在许多情况下被认为是无法治愈的，并提供了进一步的证据证明BDScs注射可提高不同动物组织中再生过程的速度和质量。

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