GTP (#gamma#S)and GDP (#beta#S) as electron donors: new wine in old bottles

Douglas A. Peterson; Daniel C. Peterson; Helen L. Reeve; Stephen L. Archer; E. Kenneth Weir

首页> 外文期刊>Life sciences >GTP (#gamma#S)and GDP (#beta#S) as electron donors: new wine in old bottles

【24h】

GTP (#gamma#S)and GDP (#beta#S) as electron donors: new wine in old bottles

机译：GTP（＃gamma＃S）和GDP（＃beta＃S）作为电子捐助者：旧瓶装新酒

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

G proteins are membrane-bound regulatory proteins which modulate the activity of ion channels and other effector systems. The GTP and GDP analogs GTP (#gamma#S) and GDP (#beta#S) have been used to study the role of G proteins in numerous physiologic systems. The prolonged effects of these analogs have been thought to be due to the face that they are nonhydrolyzable. However, in this paper we show that the GTP (#gamma#S) and GDP (#beta#S) analogs are potent reducing agents at physiologic pH. This observation suggests that previous data obtained using these compounds may need to be reinterpreted.

机译：G蛋白是与膜结合的调节蛋白，可调节离子通道和其他效应器系统的活性。 GTP和GDP类似物GTP（＃gamma＃S）和GDP（＃beta＃S）已用于研究G蛋白在众多生理系统中的作用。这些类似物的延长作用被认为是由于它们不可水解而引起的。但是，在本文中，我们证明了GTP（＃gamma＃S）和GDP（＃beta＃S）类似物在生理pH下是有效的还原剂。该观察结果表明，使用这些化合物获得的先前数据可能需要重新解释。

著录项

来源
《Life sciences》 |1999年第11期|共6页
作者
Douglas A. Peterson; Daniel C. Peterson; Helen L. Reeve; Stephen L. Archer; E. Kenneth Weir;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生命的起源;生命科学总论;
关键词
redox; GTP (; gamma; S); GDP (; beta; S); g proteins; receptors; ion channels;

机译：氧化还原;GTP（;γ;S）;GDP（;beta;S）;g蛋白;受体;离子通道;

相似文献

外文文献
中文文献
专利

1. GTP (#gamma#S)and GDP (#beta#S) as electron donors: new wine in old bottles [J] . Douglas A. Peterson, Daniel C. Peterson, Helen L. Reeve, Life sciences . 1999,第11期

机译：GTP（＃gamma＃S）和GDP（＃beta＃S）作为电子捐助者：旧瓶装新酒
2. Formation of Superstructures of a High Rank in Alloyed #beta# (B2) Solid Solution of Eutectic #beta# / #gamma# Ni-Co-Cr-Al Alloys: I. B2-> Ni_5 Al_3 Transformation in the Process of Annealing [J] . S. V. Kositsin, N. V. Kataeva, I. I. Kositsina The Physics of Metals and Metallography . 2001,第4期

机译：共晶＃beta＃/＃gamma＃Ni-Co-Cr-Al合金＃beta＃（B2）合金固溶体中高等级超结构的形成：I. B2-> Ni_5 Al_3在退火过程中的转变
3. Determination of the #beta#/#beta# + #gamma# eutectoid transition temperature in ZrO_(2-x) at variable heating/cooling rates [J] . P. J. Hayward, I. M. George Journal of Nuclear Materials: Materials Aspects of Fission and Fusion . 1999,第1a2期

机译：在可变加热/冷却速率下确定ZrO_（2-x）中的#beta＃/＃beta＃+＃gamma＃共析转变温度
4. 3.15 Construction of a #gamma# - #gamma# and #beta# - #gamma# coincidence measurement system for precise deterination of nuclear data [C] . Kazu7yoshi Furutaka, Shoji Nakamura, Hideo Harada, Symposium on nuclear data . 1999

机译：3.15构造用于精确确定核数据的＃gamma＃-＃gamma＃和＃beta＃-＃gamma＃符合测量系统
5. Effect of GTP/GDP ratio on G protein-mediated signal transduction. [D] . Fujita, Shigeo. 2004

机译：GTP / GDP比对G蛋白介导的信号转导的影响。
6. Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. [O] . K Kaibuchi, T Mizuno, H Fujioka, 1991

机译：smg p21s（ras p21样小GTP结合蛋白）的刺激性GDP / GTP交换蛋白cDNA的分子克隆和刺激性GDP / GTP交换蛋白的表征。
7. Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. [O] . Kaibuchi, K, Mizuno, T, Fujioka, H, 1991

机译：smg p21s（ras p21样小GTP结合蛋白）的刺激性GDP / GTP交换蛋白cDNA的分子克隆和刺激性GDP / GTP交换蛋白的表征。

GTP (#gamma#S)and GDP (#beta#S) as electron donors: new wine in old bottles

摘要

著录项

相似文献

相关主题

期刊订阅