• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Life sciences >AUTONOMIC CONTROL OF THE REGIONAL HEMODYNAMIC RESPONSE TO SCALD
【24h】

AUTONOMIC CONTROL OF THE REGIONAL HEMODYNAMIC RESPONSE TO SCALD

机译：对SCALD区域血流动力学响应的自动控制

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Ultrasonic flow probes were placed around the ascending aorta and each femoral artery of dogs to record cardiac index and femoral blood flow, respectively. Intravenous hexamethonium (n=5) produced 30% decreases in systemic mean arterial pressure and in cardiac index, and a 14% increase in femoral blood flow, effects that waned over time, consistent with the half-life of the agent. Without hexamethonium, hind paw scalding with boiling water for 5 sec (n=5) caused a marked increase in ipsilateral femoral artery blood flow (70.7+/-8.9 ml/min pre-burn vs 243.7+/-23.7 ml/min 5 min post-burn) that persisted for the 3 hr observation period. Contralateral femoral blood flow, systemic mean arterial pressure, and cardiac index were unchanged. Compared to burn only dogs, pre-burn treatment with hexamethonium (n=6) blunted the femoral vasodilator response to burn (78.8+/-9.7 ml/min pre-burn vs 116.5+/-7.5 ml/min 5 min post-burn). These data suggest that postganglionic autonomic nerves are at least partially responsible for mediation of the regional vasodilator response to thermal injury. [References: 13]
机译：将超声波流量探头放置在犬的升主动脉和每个股动脉周围，分别记录心脏指数和股动脉血流量。静脉注射六甲铵（n = 5）使全身平均动脉压和心脏指数下降30％，而股血流量增加14％，随着时间的流逝逐渐减弱，与该药物的半衰期一致。没有六甲铵，用沸水烫伤后爪5秒钟（n = 5）导致同侧股动脉血流量显着增加（烧伤前为70.7 +/- 8.9 ml / min，而烧伤前为243.7 +/- 23.7 ml / min）烧伤后）持续3个小时的观察期。对侧股动脉血流量，全身平均动脉压和心脏指数均未改变。与仅烧伤的狗相比，用六甲铵（n = 6）进行烧伤前治疗可减弱股骨头血管扩张剂对烧伤的反应（烧伤前为78.8 +/- 9.7 ml / min，烧伤后5 min为116.5 +/- 7.5 ml / min ）。这些数据表明神经节后自主神经至少部分负责介导对热损伤的区域性血管舒张反应。 [参考：13]

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号