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首页> 外文期刊>Life sciences >Assessing the potential of a 'color effect' for hair analysis of 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol: Analysis of a large sample of hair specimens.
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Assessing the potential of a 'color effect' for hair analysis of 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol: Analysis of a large sample of hair specimens.

机译：评估11-nor-9-羧基-Delta（9）-四氢大麻酚头发分析的“颜色效应”潜力：分析大量头发样本。

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It has been hypothesized that hair color may play a role in the concentration of various drugs of abuse in hair. Several studies have shown that melanin in hair appears to play a binding role for at least some commonly abused drugs. However, these studies have been limited by a number of factors when assessing the clinical significance of a hypothesized melanin or color effect. This study evaluates the possible effect of hair color on the concentration of 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol (c-THC) in human hair. The analysis is based on 3,886 positive c-THC hair specimens drawn from a universe of approximately 80,000 specimens of scalp hair harvested from the posterior vertex of the head. Analysis of variance of color categorization by c-THC concentration shows that c-THC concentration does not have a significant association with hair color (Hair Color F = 1.148, p =.332) and therefore does not have a demonstrable "color effect".
机译：据推测，染发可能在头发中各种滥用药物的浓度中起作用。几项研究表明，头发中的黑色素似乎对至少一些常见滥用药物起着约束作用。但是，在评估假设的黑色素或颜色效应的临床意义时，这些研究受到许多因素的限制。这项研究评估了染发对人发中11-nor-9-羧基-Delta（9）-四氢大麻酚（c-THC）浓度的可能影响。该分析基于3886个阳性c-THC头发样本，这些样本是从从头部后顶点采集的大约80,000个头皮头发样本中提取的。通过c-THC浓度对颜色分类的方差分析表明，c-THC浓度与头发颜色没有显着关联（头发颜色F = 1.148，p = .332），因此没有明显的“颜色效果”。

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