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首页> 外文期刊>Lupus >Granulomatous liver involvement in a child with systemic lupus erythematosus: A case report and review of the literature
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Granulomatous liver involvement in a child with systemic lupus erythematosus: A case report and review of the literature

机译:儿童系统性红斑狼疮肉芽肿性肝受累:一例病例报告并文献复习

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摘要

Systemic lupus erythematosus (SLE) is uncommon in young children and unusual in infancy. Although a variety of liver pathologies have been reported in SLE, presentation of this disease with granulomatous liver involvement is very rare. In this article, for the first time, we report an infant girl presenting with unexplained hepatosplenomegaly and non-necrotizing granulomatous liver involvement at the age of six months who later developed pancytopenia and proteinuria and was finally diagnosed with SLE at the age of three years. Therefore, we suggest that SLE could be considered as one of the possible differential diagnoses when infants or children present with unexplained granulomatous liver involvement.
机译:系统性红斑狼疮(SLE)在幼儿中不常见,在婴儿期也不常见。尽管在SLE中已报道了多种肝脏病理,但这种疾病伴肉芽肿性肝受累的表现非常罕见。在本文中,我们首次报道了一个婴儿女孩,在六个月大时出现原因不明的肝脾肿大和非坏死性肉芽肿性肝脏受累,后来发展为全血细胞减少症和蛋白尿症,最终在三岁时被确诊为SLE。因此,我们建议当婴儿或儿童出现无法解释的肉芽肿性肝脏受累时,SLE可被视为可能的鉴别诊断之一。

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