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Malignant melanoma: impact of superficial US on management.

机译:恶性黑色素瘤:浅表性美国对管理的影响。

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摘要

PURPOSE: To evaluate the impact of superficial ultrasonography (US) on clinical management of melanoma. MATERIALS AND METHODS: Superficial US in areas at high risk for local recurrence or nodal metastases was performed in 33 patients with cutaneous melanoma. Impact categories were assigned to each US study (n = 55): category 3, US added information that altered clinical management; category 2, US added information that did not change management; category 1, no added information and management unchanged; category 0, not helpful or was misleading. RESULTS: Twenty-two US studies (40%) were category 3: detection of nonpalpable metastases altered surgical therapy (n = 2), demonstration of pharmacodynamic response to chemotherapy (n = 5), and determination of benignancy or malignancy (n = 15). Nine (16%) were category 2: identification of nonpalpable metastases did not alter management. Twenty-two (40%) were category 1: supported clinical impression of no metastases (n = 18) or helped confirm cutaneous, subcutaneous, or nodal metastases (n = 4). Two (4%) were category 0: missed proved metastases. CONCLUSION: Superficial US affected management of melanoma by allowing detection and characterization of masses, guidance of biopsy, and assessment of pharmacodynamic response.
机译:目的:评估浅表超声检查(US)对黑素瘤临床治疗的影响。材料与方法:在33例皮肤黑色素瘤患者中,在局部复发或淋巴结转移高危区域进行了浅表超声检查。将影响类别分配给每个美国研究(n = 55):类别3,美国增加了改变临床管理的信息;第2类,美国添加了不会更改管理的信息;类别1,未添加任何信息,管理保持不变;类别0,没有帮助或具有误导性。结果:22项美国研究(40%)属于类别3:检测无法触及的转移改变的手术疗法(n = 2),证明对化疗的药效学反应(n = 5)以及确定良性或恶性(n = 15) )。 9个(16%)属于第2类:不可触及转移的识别未改变治疗。 22(40%)属于第1类:支持无转移的临床印象(n = 18)或有助于确认皮肤,皮下或淋巴结转移(n = 4)。 0类中有2个(4%):未证实转移。结论:通过允许检测和表征肿块,指导活检和评估药效学反应,美国浅表影响了黑素瘤的治疗。

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