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首页> 外文期刊>Radiology >Renal perfusion: pharmacologic changes depicted with power Doppler US in an animal model.
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Renal perfusion: pharmacologic changes depicted with power Doppler US in an animal model.

机译：肾灌注：用功率多普勒超声在动物模型中描述的药理变化。

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PURPOSE: To evaluate the ability of power Doppler ultrasonography to depict changes in renal perfusion after pharmacologic manipulations. MATERIALS AND METHODS: Six domestic swine were intubated and anesthetized. The right renal artery was catheterized for injection of epinephrine (100 micrograms) and papaverine (2 mg/kg). Intraarterial blood pressure, heart rate, and oxygen saturation were measured continuously. Longitudinal images of the kidney were obtained, and the power Doppler color map was analyzed subjectively and by computer at baseline and at the time of maximum drug effect. RESULTS: Epinephrine produced vasoconstriction with a diminished power Doppler color map and a decrease in both subjective and computer scores. After papaverine-induced vasodilatation, the power Doppler map was enhanced, as reflected by increased subjective and computer scores. CONCLUSION: The power Doppler color map reflects anticipated changes in renal perfusion after alterations in blood flow by vasoactive drugs.
机译：目的：评估功率多普勒超声描绘药理学操作后肾脏灌注变化的能力。材料与方法：对六只家猪进行了插管和麻醉。右肾动脉导管插入注射肾上腺素（100微克）和罂粟碱（2 mg / kg）。连续测量动脉内血压，心率和血氧饱和度。获得肾脏的纵向图像，并在基线和最大药物作用时通过计算机主观分析功率多普勒彩色图。结果：肾上腺素产生血管收缩，功率多普勒彩色图减弱，主观评分和计算机评分降低。罂粟碱引起的血管舒张后，力量多普勒图得到增强，这反映在主观评分和计算机评分的提高上。结论：功率多普勒彩色图反映了血管活性药物改变血流量后肾脏灌注的预期变化。

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