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首页> 外文期刊>Radiology >Airway obstruction in asthmatic and healthy individuals: inspiratory and expiratory thin-section CT findings.
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Airway obstruction in asthmatic and healthy individuals: inspiratory and expiratory thin-section CT findings.

机译：哮喘和健康个体的气道阻塞：吸气和呼气薄层CT表现。

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PURPOSE: To determine differences in computed tomographic (CT) findings in asthmatic and healthy individuals and to correlate the findings with severity of airway obstruction. MATERIALS AND METHODS: Thirty-nine asthmatic patients and 14 healthy subjects were prospectively evaluated with thin-section CT. Inspiratory CT scans were subjectively evaluated for presence of bronchial wall thickening, bronchial dilatation, and mosaic lung attenuation; expiratory scans were subjectively evaluated for presence of air trapping. Objective measurement of bronchoarterial-diameter ratio was performed on inspiratory scans. CT findings were compared with pulmonary function test results. RESULTS: Bronchial wall thickening, severe air trapping, and reduced bronchoarterial-diameter ratio were observed more commonly in asthmatic patients than in healthy subjects. Bronchial wall thickening was more prevalent among patients with severe airflow obstruction (10 of 12 readings [83%]) than in patients with normal airflow (15 of 40 readings [38%]) or mild obstruction (nine of 26 readings [35%]). Other subjectively determined CT findings did not correlate with pulmonary function test results. The mean bronchoarterial-diameter ratios +/- 1 standard deviation were 0.65 +/- 0.16 in healthy subjects and 0.60 +/- 0.16, 0.60 +/- 0.18, and 0.48 +/- 0.11 in patients with normal airflow and mild and severe obstruction, respectively. CONCLUSION: Thin-section CT is of limited value in distinguishing asthmatic patients with normal airflow or mild airflow obstruction from healthy subjects.
机译：目的：确定哮喘和健康个体的计算机断层扫描（CT）检查结果的差异，并将检查结果与气道阻塞的严重程度相关联。材料与方法：前瞻性评估了39例哮喘患者和14例健康受试者。主观评估吸气CT扫描是否存在支气管壁增厚，支气管扩张和镶嵌肺衰减。主观评估呼气扫描是否存在空气滞留。吸气扫描客观测量支气管动脉直径比。将CT检查结果与肺功能检查结果进行比较。结果：与健康受试者相比，哮喘患者更常观察到支气管壁增厚，严重的空气滞留和降低的支气管动脉直径比。严重气流阻塞（12个读数中的10个[83％]）比正常气流（40个读数中的15个[38％]）或轻度阻塞（26个读数中的9个[35％]）的患者支气管壁增厚更为普遍。 ）。其他主观确定的CT表现与肺功能检查结果无关。健康受试者的平均支气管动脉直径比+/- 1标准偏差为0.65 +/- 0.16，气流正常且轻度和严重阻塞的患者为0.60 +/- 0.16、0.60 +/- 0.18和0.48 +/- 0.11 ， 分别。结论：薄层CT对于将正常气流或轻度气流阻塞的哮喘患者与健康受试者区分开来的价值有限。

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