Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis.

Wehrli FW; Ford JC; Haddad JG

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Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis.

机译：骨质疏松：使用定量MR成像进行临床评估以进行诊断。

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PURPOSE: To determine if the magnetic resonance (MR) imaging effective transverse relaxation rate (R2*) of trabecular bone marrow is lowered in osteoporosis. MATERIALS AND METHODS: R2* was measured in 146 women. Control subjects (n = 77; mean age, 46.6 years) had high mean spinal bone mineral densities (BMDs) and no vertebral deformities. Patients with spinal osteoporosis (n = 59; mean age, 59.7 years) had at least one thoracic vertebral deformity and/or low BMDs. RESULTS: R2* was lower in patients for L-2 through L-5 (P < .001). Average R2* of L-3 through L-5 (R2*av) was the best discriminator (64.79 sec-1 +/- 1.18 [standard error] for control subjects vs 53.39 sec-1 +/- 1.24 for patients; P < .0001). R2*av decreased with age in control subjects. The difference in R2*av in a subset of 38 age-matched pairs of patients and control subjects was 8.25 sec-1 (P < .0001). Subjects with deformities had lower 52*av than did control subjects (52.3 sec-1 +/- 1.6 vs 62.5 sec-1 +/- 1.1, P < .0001). R2*av was correlated with mean BMD (r = .54, P < .0001). CONCLUSION: Patients with osteoporosis have lower R2*s in vertebral marrow.

机译：目的：确定在骨质疏松症中，骨小梁骨髓的磁共振（MR）成像有效横向松弛率（R2 *）是否降低。材料与方法：在146位女性中测量了R2 *。对照组（n = 77;平均年龄，46.6岁）的平均脊椎骨矿物质密度（BMD）高，无椎体畸形。脊柱骨质疏松症患者（n = 59;平均年龄，59.7岁）患有至少一种胸椎畸形和/或BMD低。结果：L-2至L-5患者的R2 *较低（P <.001）。 L-3至L-5的平均R2 *（R2 * av）是最好的区分因素（对照组为64.79 sec-1 +/- 1.18 [标准误]，而患者为53.39 sec-1 +/- 1.24; P < .0001）。在对照组中，R2 * av随着年龄的增长而降低。在38位年龄匹配的患者和对照组中，R2 * av的差异为8.25 sec-1（P <.0001）。畸形受试者的52 * av低于对照受试者（52.3 sec-1 +/- 1.6与62.5 sec-1 +/- 1.1，P <.0001）。 R2 * av与平均BMD相关（r = .54，P <.0001）。结论：骨质疏松症患者的椎体R2 * s较低。

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《Radiology》 |1995年第3期|共11页
作者
Wehrli FW; Ford JC; Haddad JG;
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正文语种 eng
中图分类放射医学;
关键词
Magnetic Resonance Imaging; Osteoporosis; Spinal Diseases; 磁共振成像; 骨质疏松; 脊柱疾病;

机译：Magnetic Resonance Imaging;Osteoporosis;Spinal Diseases;磁共振成像;骨质疏松;脊柱疾病;

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1. Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis. [J] . Wehrli FW, Ford JC, Haddad JG Radiology . 1995,第3期

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机译：用于骨质疏松症和其他临床应用的高分辨率高场定量平行磁共振成像。
6. Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia [O] . Sara Guerri, Daniele Mercatelli, Maria Pilar Aparisi Gómez, 2018

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机译：健康监测中的图像：蜱传疾病媒介和莱姆病临床诊断。

Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis.

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