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Quantitative CT evaluation of adrenal gland masses: a step forward in the differentiation between adenomas and nonadenomas?

机译：肾上腺肿块的CT定量评估：在区分腺瘤和非腺瘤方面向前迈进了一步？

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PURPOSE: To assess the attenuation of the adrenal gland with computed tomography (CT) before and after multiple phases of contrast enhancement in both control subjects and patients with adenomas and nonadenomas. MATERIALS AND METHODS: Seventy-two patients with 78 adrenal masses (41 adenomas, 37 nonadenomas) underwent helical CT. Forty subjects served as controls. Unenhanced CT was performed followed by enhanced CT at 30, 60, 90, and 180 seconds and 30 minutes. RESULTS: At unenhanced CT, mean attenuation was 4 HU +/- 16 for adenomas compared with 37 HU +/- 12 for the nonadenomas (P < .001) and 24 HU +/- 3 for normal glands. Although the mean attenuation of nonademonas was significantly greater than that of adenomas on 60- and 90-second scans (P < .001), there was greater overlap in attenuation of the adenomas and nonadenomas than on unenhanced images. At 180 seconds, nonadenomas had higher attenuation than adenomas (73 HU +/- 17 vs 41 HU +/- 18; P < .001). At 30 minutes, all adenomas had attenuation less than 37 HU, whereas all nonadenomas had attenuation greater than 41 HU. CONCLUSION: Delayed-enhanced CT scans obtained 30 minutes after administration of contrast material can enable differentiation of adenomas and nonadenomas.
机译：目的：评估在多个对比增强阶段之前和之后，在对照受试者以及患有腺瘤和非腺瘤的患者中，通过计算机断层扫描（CT）评估肾上腺的衰减。材料与方法：72例肾上腺肿块（41例腺瘤，37例非腺瘤）患者接受了螺旋CT检查。 40名受试者作为对照。在30、60、90和180秒和30分钟时进行CT增强检查，然后进行增强CT检查。结果：在未增强的CT下，腺瘤的平均衰减为4 HU +/- 16，而非腺瘤的平均衰减为37 HU +/- 12（P <.001），正常腺体为24 HU +/- 3。尽管在60秒和90秒扫描中，腺瘤的平均衰减显着大于腺瘤（P <.001），但与未增强图像相比，腺瘤和非腺瘤的衰减重叠更大。在180秒时，非腺瘤的衰减要比腺瘤高（73 HU +/- 17对41 HU +/- 18; P <.001）。在30分钟时，所有腺瘤的衰减均小于37 HU，而所有非腺瘤的衰减均大于41 HU。结论：造影剂给药30分钟后获得的延迟增强CT扫描可以区分腺瘤和非腺瘤。

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