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首页> 外文期刊>Radiology >HIV-associated human herpesvirus 8-positive primary lymphomatous effusions: radiologic findings in six patients.
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HIV-associated human herpesvirus 8-positive primary lymphomatous effusions: radiologic findings in six patients.

机译：与HIV相关的人类疱疹病毒8阳性原发性淋巴瘤积液：6例患者的影像学表现。

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摘要

PURPOSE: To define the imaging features of body cavity-based lymphoma (BCBL) related to the acquired immunodeficiency syndrome. This is a peculiar type of non-Hodgkin lymphoma harboring infection by human herpesvirus 8 (HHV-8) and displaying a peculiar tropism for the serous body cavities. MATERIALS AND METHODS: At diagnosis of BCBL, six consecutive patients were investigated with radiography of the chest and conventional computed tomography (CT) of the chest and abdomen. For all patients, clinical features and results of biologic characterization of the lymphoma were also available. RESULTS: In all patients, chest radiographs displayed bilateral or unilateral pleural effusion in the absence of parenchymal opacities or mediastinal enlargement. CT scans confirmed chest radiographic findings and revealed a slight thickening of the parietal pleura in all patients and a pericardial thickening in four patients. CT also depicted pericardial and abdominal effusions in five and two patients, respectively, in the absence of solid tumor masses or parenchymal abnormalities. CONCLUSION: BCBL must be included among the differential diagnoses of serous effusions detected radiologically in individuals infected with the human immunodeficiency virus (HIV). Since the combination of serous effusion, slight serosal thickening, and absence of solid masses is compatible with, though not specific for, BCBL in the context of HIV infection, radiologic findings need to be complemented by a detailed biologic and virologic characterization of tumor cells.
机译：目的：定义与获得性免疫缺陷综合症有关的体腔淋巴瘤（BCBL）的影像学特征。这是一种特殊类型的非霍奇金淋巴瘤，具有人类疱疹病毒8（HHV-8）的感染能力，并表现出浆液腔特有的嗜性。材料与方法：在诊断BCBL时，对连续6例患者进行了胸部X线摄影和常规胸部和腹部X线断层扫描（CT）检查。对于所有患者，淋巴瘤的临床特征和生物学特征结果也可提供。结果：在所有患者中，胸部X光片显示双侧或单侧胸腔积液，没有实质性混浊或纵隔肿大。 CT扫描证实了胸部影像学发现，并发现所有患者的壁层胸膜略有增厚，而四位患者的心包增厚。 CT还分别描绘了5例和2例患者的心包和腹腔积液，没有实体瘤或实质性异常。结论：BCBL必须包括在通过人类免疫缺陷病毒（HIV）感染的个体中通过放射学检测出的浆液积液的鉴别诊断中。由于浆液积液，轻微的浆膜增厚和不存在实体块的组合在HIV感染的情况下与BCBL兼容，尽管不是特异性的，所以放射学上的发现需要以肿瘤细胞的详细生物学和病毒学特征为补充。

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