Signaling cascades initiated by TSLP-mediated signals in different cell types

YuX.; LiH.; RenX.

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Signaling cascades initiated by TSLP-mediated signals in different cell types

机译：TSLP介导的信号在不同细胞类型中引发的信号级联

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Thymic stromal lymphopoietin (TSLP) has been well characterized as a consequence of its ability to modulate allergic and neoplastic diseases. However, downstream signaling mediated by TSLP varies significantly between the cell type and species examined. Since this observation is often overlooked and in some cases ignored, this review aims to consolidate the molecular pathways activated by TSLP receptors expressed by various human and mouse cell types.

机译：胸腺基质淋巴细胞生成素（TSLP）具有调节过敏性和肿瘤性疾病的能力，因此已得到很好的表征。但是，由TSLP介导的下游信号在细胞类型和所检测物种之间有很大差异。由于这种观察经常被忽视，在某些情况下被忽略，因此本综述旨在巩固由各种人类和小鼠细胞类型表达的TSLP受体激活的分子途径。

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《Cellular immunology》 |2012年第2期|共6页
作者
YuX.; LiH.; RenX.;
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正文语种 eng
中图分类细胞生物学;
关键词
Immune tolerance; JAK; Signaling pathways; STAT; Th2 polarization; Thymic stromal lymphopoietin; Tregs;

机译：免疫耐受;JAK;信号通路;STAT;Th2极化;胸腺基质淋巴细胞生成素;Tregs;

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专利

1. Signaling cascades initiated by TSLP-mediated signals in different cell types [J] . YuX., LiH., RenX. Cellular immunology . 2012,第2期

机译：TSLP介导的信号在不同细胞类型中引发的信号级联
2. A primer on TCR signaling: Ligation of the TCR initiates multiple signaling cascades that direct the fate of thymocytes and T cells [J] . Nature immunology . 2014,第9期

机译：TCR信号传导入门：TCR的连接引发多个信号传导级联，这些信号传导指导胸腺细胞和T细胞的命运
3. NRF2/SHH signaling cascade promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma (vol 476, pg 48, 2020) [J] . Leung Hoi Wing, Lau Eunice Yuen Ting, Leung Carmen Oi Ning, Cancer letters . 2021,第1期

机译：NRF2 / SHH信号级联促进肝细胞癌中肿瘤引发细胞谱系和耐药性（Vol 476，PG 48,2020）
4. Gold-coated Liposomes Encapsulating Signaling Molecules for Initiating Cellular Communication [C] . G.V. Orsinger, M. Romanowski Annual NSTI nanotechnology conference and expo . 2013

机译：包被信号分子的金涂层脂质体，用于启动细胞通讯
5. HIV initiates multiple signaling cascades required for effective replication. [D] . Kelly, Jeremy. 2010

机译：HIV启动了有效复制所需的多个信号级联。
6. Complex Oncogenic Signaling Networks Regulate Brain Tumor-Initiating Cells and Their Progenies: Pivotal Roles of Wild-Type EGFR EGFRvIII Mutant and Hedgehog Cascades and Novel Multitargeted Therapies [O] . Murielle Mimeault, Surinder K. Batra -1

机译：复杂的致癌信号网络调节脑肿瘤起始细胞及其后代：野生型EGFREGFRVIII突变体和刺猬级联和新型多目标疗法的枢轴作用
7. Complex Oncogenic Signaling Networks Regulate Brain Tumor-Initiating Cells and Their Progenies: Pivotal Roles of Wild-Type EGFR, EGFRvIII Mutant and Hedgehog Cascades and Novel Multitargeted Therapies [O] . Murielle Mimeault, Surinder K. Batra 2011

机译：复杂的致癌信号网络调节脑肿瘤起始细胞及其后代：野生型EGFR，EGFRVIII突变体和刺猬级联和新型多目标疗法的枢轴作用

Signaling cascades initiated by TSLP-mediated signals in different cell types

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