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Use of Tl-201 to detect untreated pediatric Hodgkin disease.

机译:使用Tl-201检测未治疗的小儿霍奇金病。

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PURPOSE: To evaluate the usefulness of thallium-201 scintigrams in depiction of supradiaphragmatic lymphadenopathy associated with newly diagnosed Hodgkin disease in pediatric patients. MATERIALS AND METHODS: Thallium-201 and gallium-67 scans of the chest and neck were obtained in 33 consecutive patients. Mediastinal, cervical, supraclavicular, and axillary lymph node activity was evaluated by independent raters, and results were compared in a blinded fashion with those on chest computed tomographic (CT) scans. RESULTS: Gallium and thallium scans demonstrated similar accuracy in depiction of CT-defined mediastinal masses. The kappa statistic indicated moderate to strong agreement with CT results. Similarly, there was no statistically significant difference between the accuracy of thallium and gallium scans in depiction of extramediastinal lymphadenopathy. CONCLUSION: Thallium scintigraphy is effective for depiction of lymphadenopathy in pediatric patients with untreated Hodgkin disease. Serial thalliumstudies may provide an alternative to gallium scans in monitoring response to treatment.
机译:目的:评估al201闪烁图在儿科患者新诊断霍奇金病相关的sup上淋巴结病的描述中的有效性。材料与方法:连续33例患者对胸部和颈部进行了hall 201和镓67扫描。通过独立的评估者评估了纵隔,宫颈,锁骨上和腋窝淋巴结的活动,并以盲法将其结果与胸部CT(CT)扫描结果进行了比较。结果:镓和th扫描显示出CT定义的纵隔肿块的准确性相似。卡伯统计表明与CT结果具有中度至强烈一致性。同样,在纵隔外淋巴结病的描述中,and和镓扫描的准确性之间也没有统计学上的显着差异。结论:T闪烁显像可以有效地描述小儿霍奇金病患者的淋巴结病。连续的th研究可能会提供替代镓扫描的方法来监测对治疗的反应。

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