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首页> 外文期刊>Radiology >Aortic and Hepatic Enhancement and Tumor-to-Liver Contrast: Analysis of the Effect of Different Concentrations of Contrast Material at Multi-Detector Row Helical CT.
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Aortic and Hepatic Enhancement and Tumor-to-Liver Contrast: Analysis of the Effect of Different Concentrations of Contrast Material at Multi-Detector Row Helical CT.

机译：主动脉和肝脏的增强以及肿瘤与肝脏之间的对比：在多检测器行螺旋CT上不同浓度的对比材料的影响分析。

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摘要

PURPOSE: To investigate the effect of different iodine concentrations of contrast material on aortic and hepatic enhancement and the detectability of hypervascular hepatocellular carcinoma (HCC) with multi-detector row computed tomography (CT) and a uniphasic contrast material injection technique. MATERIALS AND METHODS: Two hundred one patients with known or who were suspected of having HCC underwent multi-detector row CT; 58 patients with hypervascular HCC were identified. First-, second-, and third-phase scanning was started with the aortic arrival times plus 15 seconds, plus 30 seconds, and plus 105 seconds, respectively. All patients were assigned randomly into two groups. Patients in groups A and B received iopamidol with an iodine concentration of 300 mg/mL and 370 mg/mL, respectively, with the same total iodine load per patient per body weight. The liver and aorta enhancement and tumor-to-liver contrast (TLC) were measured. Depiction of hepatic arteries was evaluated visually by two radiologists. RESULTS: During the first phase, aortic enhancement was significantly (P <.01) higher in group B, with no significant difference in hepatic enhancement between the two groups. During the second phase, aortic enhancement was significantly (P <.01) higher in group A, with no significant difference in hepatic enhancement. The TLC was significantly (P <.01) higher in group B during the first phase, but there was no significant difference between the two groups during the second phase. There was no significant difference in any parameters between the two groups during the third phase. Depiction of the hepatic arteries in group B was significantly (P <.05) superior to that in group A. CONCLUSION: In the arterial phase, administration of a higher concentration of contrast material is effective for a significantly higher TLC. Copyright RSNA, 2002
机译：目的：利用多排行计算机断层扫描（CT）和单相造影剂注射技术，研究不同碘浓度的造影剂对主动脉和肝脏增强的影响，以及高血管肝细胞癌（HCC）的可检测性。材料与方法：201名已知或怀疑患有肝癌的患者接受了多排行CT检查。确定了58例高血管HCC患者。开始第一，第二和第三阶段的扫描时，主动脉到达时间分别加15秒，30秒和105秒。将所有患者随机分为两组。 A组和B组的患者分别接受碘浓度分别为300 mg / mL和370 mg / mL的碘帕醇，每位患者每体重的总碘负荷相同。测量肝和主动脉增强和肿瘤-肝脏对比（TLC）。两位放射科医生对肝动脉的描绘进行了视觉评估。结果：在第一阶段，B组的主动脉增强显着（P <.01）高，两组之间的肝增强无显着差异。在第二阶段，A组的主动脉增强显着（P <.01）高，而肝增强无显着差异。 B组在第一阶段的TLC显着较高（P <.01），但在第二阶段在两组之间没有显着差异。在第三阶段，两组之间的任何参数都没有显着差异。 B组的肝动脉表现明显优于A组（P <.05）。结论：在动脉期，给予较高浓度的造影剂对于显着提高TLC是有效的。 RSNA，2002年版权所有

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