...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Radiology >Bone loss in patients with chronic renal disease: prediction with quantitative bone scintigraphy with SPECT.
【24h】

Bone loss in patients with chronic renal disease: prediction with quantitative bone scintigraphy with SPECT.

机译：慢性肾脏疾病患者的骨丢失：采用SPECT定量骨闪烁显像术进行预测。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To determine whether quantitative bone scintigraphy (QBS) with single-energy photon emission computed tomography (SPECT) can help predict which patients with chronic renal disease will show bone mineral density (BMD) loss. MATERIALS AND METHODS: In 18 patients, the percentage of injected dose of technetium-99m methylene diphosphonate per cubic centimeter of bone was measured with QBS SPECT in the lumbar vertebrae and femoral neck. The differences in BMD over an average of 20 months were measured and compared with SPECT measurements. QBS values were also compared with serum bone turnover markers. RESULTS: There was a negative correlation (r = -.54, P < .05 for the lumbar spine and r = -.60, P < .01 for the femoral neck) between QBS values and bone loss. Positive and negative predictive values, sensitivity, and specificity of QBS for bone loss in the lumbar spine were 78%, 71%, 78%, and 71%, respectively, and in the femoral neck, 82%, 100%, 100%, and 78%, respectively. Differences between predictive values of serum bone turnover markers were not statistically significant. CONCLUSION: QBS with SPECT enabled prediction of rapid bone loss in patients with renal disease.
机译：目的：确定采用单能光子发射计算机断层扫描（SPECT）的定量骨闪烁扫描（QBS）是否可以帮助预测哪些慢性肾脏病患者会出现骨矿物质密度（BMD）下降。材料与方法：在18例患者中，使用QBS SPECT测量腰椎和股骨颈中每立方厘米骨中99m甲基二膦酸99的注射剂量百分比。测量了平均20个月的BMD差异，并将其与SPECT测量进行了比较。还将QBS值与血清骨转换标志物进行了比较。结果：QBS值与骨丢失之间存在负相关（r = -.54，P <.05，腰椎，r = -.60，P <.01，股骨颈）。腰椎骨丢失的阳性和阴性预测值，QBS的敏感性和特异性分别为78％，71％，78％和71％，而在股骨颈中，分别为82％，100％，100％，和78％。血清骨转换标志物的预测值之间的差异无统计学意义。结论：带SPECT的QBS能够预测肾病患者快速骨丢失。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号