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首页> 外文期刊>Cell cycle >Akt1 in endothelial cell and angiogenesis.
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Akt1 in endothelial cell and angiogenesis.

机译:Akt1在内皮细胞和血管生成中的作用。

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摘要

Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the expression and/or activity of various pro- and anti-angiogenic factors and Akt isoforms (Akt1, Akt2 and Akt3) have been proposed as therapeutic targets for angiogenesis-related anomalies such as cancer and ischemic injury.
机译:Akt,也称为蛋白激酶B(PKB),调节细胞的基本功能,例如迁移,增殖,分化,凋亡和代谢。 Akt影响各种促血管生成因子和抗血管生成因子的表达和/或活性,并且已提出Akt亚型(Akt1,Akt2和Akt3)作为与血管生成相关异常(例如癌症和缺血性损伤)的治疗靶标。

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